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Table 1 Characteristics and comparison of COPD and healthy subject groups

From: Evaluation of psychological and physiological predictors of fatigue in patients with COPD

 

COPD (n = 74)

Healthy (n = 35)

p value

MFI 20 General Fatigue

13 (5)

8 (4)

p < 0.001

MFI 20 Physical Fatigue

16 (5.25)

7 (5)

p < 0.001

MFI 20 Reduced Activity

13.5 (6)

6 (5)

p < 0.001

MFI 20 Reduced Motivation

10 (6)

6 (4)

p < 0.001

MFI 20 Mental Fatigue

8 (7)

6 (4)

p = 0.008

% FEV1

46.5(20.0)

96.5(13.2)

p < 0.001

FEV1/FVC ratio

0.44 (0.13)

0.78(0.1)

p < 0.001

Age (yrs)

69.9 (8.4)

67.11 (8.8)

NS

BMI (kg/m2)

26.2 (5.4)

25.2 (3.4)

NS

FFMI (kg/m2)

18.2 (2.6)

17.9 (2.2)

NS

Depression (HADS)

6 (5)

1 (3)

p < 0.001

Anxiety (HADS)

7 (6)

3 (4)

p < 0.001

Peak Tq (% BW)

38.6 (12.0)*

51.6 (14.5)

p < 0.001

ISWT (m)

343.3 (183.9) *

-

-

Post walk SpO2 (%)

90.0(5.9)*

-

-

Borg exertion (RPE)

13(2.0)*

-

-

IL 6 (pg/mL) (n = 57)

5.4(5.9) *

-

-

MRC dyspnoea score

3 (2)

-

-

SGRQ

56.0 (27.4)

-

-

  1. Data presented as median (IQR) for MFI 20-Multidimensional Fatigue Inventory, HADS - Hospital Anxiety and Depression scale, SGRQ - Saint George's Respiratory Questionnaire, total score, Borg exertion, MRC score or mean (SD) for % FEV1 - % predicted forced expiratory volume in one second, FEV1/FVC - Forced Expiratory Volume in one second/Forced Vital Capacity, BMI - Body Mass Index; FFMI - Fat Free Mass Index; Peak Tq (% BW) - quadriceps peak torque (% Body Weight), ISWT - Incremental Shuttle walk test, SpO2 - Percutaneous arterial oxygen saturation. *not measured in home-assessed patients (n = 59).
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BMC Pulmonary Medicine

ISSN: 1471-2466

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