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Table 1 Characteristics and comparison of COPD and healthy subject groups

From: Evaluation of psychological and physiological predictors of fatigue in patients with COPD

  COPD (n = 74) Healthy (n = 35) p value
MFI 20 General Fatigue 13 (5) 8 (4) p < 0.001
MFI 20 Physical Fatigue 16 (5.25) 7 (5) p < 0.001
MFI 20 Reduced Activity 13.5 (6) 6 (5) p < 0.001
MFI 20 Reduced Motivation 10 (6) 6 (4) p < 0.001
MFI 20 Mental Fatigue 8 (7) 6 (4) p = 0.008
% FEV1 46.5(20.0) 96.5(13.2) p < 0.001
FEV1/FVC ratio 0.44 (0.13) 0.78(0.1) p < 0.001
Age (yrs) 69.9 (8.4) 67.11 (8.8) NS
BMI (kg/m2) 26.2 (5.4) 25.2 (3.4) NS
FFMI (kg/m2) 18.2 (2.6) 17.9 (2.2) NS
Depression (HADS) 6 (5) 1 (3) p < 0.001
Anxiety (HADS) 7 (6) 3 (4) p < 0.001
Peak Tq (% BW) 38.6 (12.0)* 51.6 (14.5) p < 0.001
ISWT (m) 343.3 (183.9) * - -
Post walk SpO2 (%) 90.0(5.9)* - -
Borg exertion (RPE) 13(2.0)* - -
IL 6 (pg/mL) (n = 57) 5.4(5.9) * - -
MRC dyspnoea score 3 (2) - -
SGRQ 56.0 (27.4) - -
  1. Data presented as median (IQR) for MFI 20-Multidimensional Fatigue Inventory, HADS - Hospital Anxiety and Depression scale, SGRQ - Saint George's Respiratory Questionnaire, total score, Borg exertion, MRC score or mean (SD) for % FEV1 - % predicted forced expiratory volume in one second, FEV1/FVC - Forced Expiratory Volume in one second/Forced Vital Capacity, BMI - Body Mass Index; FFMI - Fat Free Mass Index; Peak Tq (% BW) - quadriceps peak torque (% Body Weight), ISWT - Incremental Shuttle walk test, SpO2 - Percutaneous arterial oxygen saturation. *not measured in home-assessed patients (n = 59).