Action Plan to enhance self-management and early detection of exacerbations in COPD patients; a multicenter RCT

BMC Pulmonary Medicine

Table 1 Characteristics of studies evaluating isolated effects of an AP as an addition to care as usual.

	Current study	Watson	Wood-Baker	McGeoch
*Procedure*
Recruitment	OC + GP	GP	GP	GP
Pilot-study	+	+	-	+
Intervention
- Early contact	+	+	+	+
- Self-initiation drugs	-	+	+	+
- Reinforcement	+	-	-	-
Outcome	exa-rt	SGRQ	SGRQ	SGRQ
*Validity*
Randomization	individual	individual	clustered	clustered
Blinding	pt + inv	-	-	-
Stratification	by centre	-	-	-
*Statistics*
Follow-up (mths)	6	6	12	12
n		56	102	151
Powered on	Δ exa-rt = 1	Δ SGRQ = 5.7	Δ SGRQ = 4	Δ SGRQ = 4
SSC	245	124	124	160

OC, outpatient clinic; GP, general practice; exa-rt, exacerbation recovery time; SGRQ, St George respiratory questionnaire n, number of patients; SSC, sample size calculation; pt, patient; inv, investigator.

ISSN: 1471-2466