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Table 5 Multivariate Cox proportional hazards analysis for survival adjusted for GAP-stage

From: Treatment of acute exacerbation of idiopathic pulmonary fibrosis with direct hemoperfusion using a polymyxin B-immobilized fiber column improves survival

Variable

Hazard ratio

95% CI

p value

  

Lower

Upper

 

Extent score on HRCT before AE

1.177

0.982

1.409

0.078

Period from admission to commencement of treatments for AE, day

1.092

0.974

1.224

0.132

PMX-DHP, +

0.345

0.127

0.936

0.037

ΔP/F ratio 2 days after commencement of treatments for AE

0.989

0.982

0.997

0.004

ΔLDH 2 days after commencement of treatments for AE, IU/L

1.007

1.002

1.013

0.007

  1. AE = acute exacerbation; HRCT = high-resolution computed tomography; PMX-DHP = direct hemoperfusion with a polymyxin B-immobilized fiber column; P/F = PaO2/FiO2; LDH = lactate dehydrogenase.