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Table 1 Patient characteristics

From: Poor sleep quality is associated with exercise limitation in precapillary pulmonary hypertension

 

IPAH

CTEPH

Number of patients

52

64

Age (yrs.)

58.2 ± 2.0

62.7 ± 1.7

Females (n/%)

39/75.0

39/60.9

BMI (kg/m2)

26.1 ± 0.9

27.4 ± 0.7

NYHA FC

2.6 ± 0.1

2.6 ± 0.1

BNP (pg/ml)

171 ± 34

120 ± 29

6MWT distance (m)

393 ± 20

375 ± 14

Mean PAP (mm Hg)

45.3 ± 1.9

42.0 ± 1.5

PVR (dyn)

718 ± 62

647 ± 41

CI (l/min/m2)

2.7 ± 0.1

2.3 ± 0.1

CVP (mm Hg)

6.2 ± 0.6

6.2 ± 0.5

PCWP (mm Hg)

8.5 ± 0.5

8.9 ± 0.4

FEV1 (% of pred.)

81.9 ± 3.0

79.0 ± 2.3

IVC (% of pred.)

92.5 ± 2.9

87.7 ± 1.9

FEV1/IVC (% of pred.)

91.4 ± 1.6

92.1 ± 1.6

DLCO (% of pred.)

70.5 ± 2.1

74.6 ± 1.9

pO2 (mm Hg)

68.2 ± 1.6

65.9 ± 1.1

pCO2 (mm Hg)

34.3 ± 0.8

35.7 ± 0.8

LTOT (n / %)

20/38.5

26/40.6

Oral anticoagulation (n/%)

37/71.2

63/98.4

Diuretics (n/%)

43/82.7

47/73.4

No vasodilator therapy (n/%)

11/21.2

16/25.0

Vasodilator monotherapy (n/%)

24/46.2

33/51.6

Vasodilator combination therapy (n/%)

17/32.7

15/23.4

  1. Abbreviations:
  2. BMI: body mass index, BNP : brain natriuretic peptide, CI: cardiac index, CTEPH: chronic thromboembolic pulmonary hypertension, CVP: central venous pressure, DLCO: diffusion capacity for carbon monoxide, FEV1: forced exspiratory volume in one second, IPAH: idiopathic pulmonary arterial hypertension, IVC: inspiratory vital capacity, LTOT: long-term oxygen therapy, NYHA FC: New York Heart Association functional class, PAP: pulmonary artery pressure, PCWP: pulmonary capillary wedge pressure, pO2 / pCO2: partial pressure of oxygen and carbon dioxide, PVR: pulmonary vascular resistance, 6MWT: six-minute walk test.