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Table 2 Summary of investigations for the diagnosis of Hypersensitivity pneumonitis

From: Working with argan cake: a new etiology for hypersensitivity pneumonitis

Before specific challenge After specific challenge *
Cases Physical examination Chest X rays DLCO Symptoms suggestive of HP DLCO (variation) % predicted CT Scan BAL Conclusion
1 normal normal 89% Yes 78% (-11%) No specific abnormalities 600000/mL 25.5% lymphocytes HP
2 normal normal 118% Yes 120% / / ODTS
3 normal normal 63% Yes 61% Emphysema 935000/mL 5% lymphocytes ODTS
4 normal normal 88% Yes 62% (-22%) Localized Ground-glass opacities 600000/mL 18% lymphocytes (not available) HP
5 normal normal 68% Yes 79% / / ODTS
6 normal normal 85% / / / / /
7 normal normal 79% / / / / /
8 normal normal 86% / / / / /
9 normal normal 95% Yes 94% / / ODTS
  1. * one-hour challenge (D0) to argan cakes at the workplace, only performed in the 6 subjects with flu-like symptoms in the 8 hours following argan handling.
  2. at day 2 after challenge.
  3. at day 4 after challenge-, only performed in subjects with significant features either on HRCT scan (ground-glass opacities) or pulmonary function tests (more than 10% decrease of DLCO after challenge).
  4. /: not performed.
  5. HP: Hypersensitivity Pneumonitis, ODTS: Organic Dust Toxic Syndrome.