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Table 4 Diagnostic values of D0 albumin and CRP for maximum Berlin and LIS categories within one week after new onset fever in critically ill patients

From: Albumin rather than C-reactive protein may be valuable in predicting and monitoring the severity and course of acute respiratory distress syndrome in critically ill patients with or at risk for the syndrome after new onset fever

 

AUROC

95% CI

P-value

Optimal cutoff

SN

SP

PPV

NPV

Maximum Berlin ≥1 (N = 59)

        

Albumin

0.65

0.53-0.76

0.01

<20 g/L

71

58

71

58

Maximum Berlin ≥2 (N = 50)

        

Albumin

0.63

0.52-0.74

0.02

<20 g/L

72

53

61

65

CRP

0.62

0.51-0.74

0.03

>138 mg/L

54

76

69

62

Maximum LIS >1.0 (N = 95)

        

CRP

0.82

0.64-1.00

0.002

>81 mg/L

77

80

99

15

Maximum LIS >2.5 (N = 34)

        

Albumin

0.62

0.51-0.73

0.04

<22 g/L

91

31

41

87

  1. Abbreviations: AUROC-area under the curve; ARDS-acute respiratory distress syndrome; CI-confidence interval; CRP-C-reactive protein; LIS- lung injury score; NPV-negative predictive value; PPV-positive predictive value; SN-sensitivity; SP- specificity.