Figure 5From: Hypoxia down-regulates expression of secretory leukocyte protease inhibitor in bronchial epithelial cells via TGF-β1Schematic model of hypoxia-driven SLPI expression. During normal oxygenation, the bronchial epithelium constitutively secretes SLPI, both apically and baso-laterally. When the oxygen concentrations decrease, the epithelium increases its expression of TGF-β1, which in turn down-regulates SLPI production.Back to article page