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Figure 7 | BMC Pulmonary Medicine

Figure 7

From: Safety and performance analysis of acriflavine and methylene blue for in vivo imaging of precancerous lesions using fibered confocal fluorescence microscopy (FCFM): an experimental study

Figure 7

ROC curves for the diagnosis of high-grade lesions, using acriflavine (7A) and methylene blue (7B). A With acriflavine FCFM, using a threshold cell diameter <13 μm, sensitivity was 88.9%, and specificity was 88.9% for the diagnosis of “severe dysplasia/carcinoma”. B With methylene blue FCFM, a threshold cell diameter <30 μm, sensitivity was 94.7%, and specificity 97% for the diagnosis of “severe dysplasia/carcinoma”.

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