# Table 4 Lung Function parameters in the first survey and annual changes (mean and C.I. 95%) adjusted for height and gender with multiple regression analysis

2003 Δ/year P<
Mean Mean model
(C.I.) (C.I.)
FEV 1 (ml) No symptoms 1108.8 181.9 NS
(1087.6-1129.9) (176.0 -187.9)
Early transient 1122.3 186.9
(1032.2-1212.4) (161.8 - 212.1)
Late onset 1105.7 171.5
(1045.31 -166.0) (154.6 - 188.4)
Persistent 1100.2 172.0
(1030.5 - 1169.9) (152.4 - 191.5)
FVC (ml) No symptoms 1121.4 233.8 (228.4 - 239.3) NS
(1100.6 - 1142.1)
Early transient 1159.3 232.2
(1072.7-1245.8) (208.4 - 255.9)
Late onset 1134.6 229.0
(1072.3 - 1197.0) (212.5 - 245.4)
Persistent 1151.5 234.9
(1074.3 - 1228.7) (214.5 - 255.4)
FEV 1 /FVC (%) No symptoms 96.5 −1.5 *
(95.9 - 97.2) (−1.7 - -1.4)
Early transient 94.2 −1.1
(91.5 - 97.0) (−1.7 - -0.6)
Late onset 96.7 −1.8
(94.9 - 98.5) (−2.2 - -1.4)
Persistent 95.9 −2.0 *
(93.8 - 98.0) (−2.4 - -1.6)
FEF 25–75 (ml/s) No symptoms 1621.9 157.4 ***
(1580.6 - 1663.1) (146.8 - 168.0)
Early transient 1531.5 158.6
(1353.4 - 1709.6) (113.0 - 204.1)
Late onset 1570.3 135.5 *
(1447.4 - 1693.1) (104.0 - 166.9)
Persistent 1506.4 113.7 **
(1354.2 - 1658.6) (74.7 - 152.7)
1. - * P < 0.05.
2. - ** P < 0.01.
3. Δ: (Differences between the 2 occasions/Years of follow-up)
4. Note: the statistical significativity in the last column is for the model; the * in the cell reports the significativity of the difference of the mean compared with the asymptomatic subjects mean.