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Table 1 Baseline characteristics of pediatric patients with severe uncontrolled asthma (N = 36) treated at a referral center for asthma in Brazil

From: Phenotypes of severe asthma among children and adolescents in Brazil: a prospective study

Variable

n (%)

Median (IQR)

Female gender

23 (63.9)

 

Age (years)

 

11.6 (6.2 to 17.8)

Height (Z score)

 

0.05 (−2.66 to 1.00)

BMI (Z score)

 

−0.48 (−2.90 to 1.84)

Well-controlled home environment

9 (25.0)

 

Severe persistent allergic rhinitis

35 (97.2)

 

Severe exacerbations in the last 12 months

 

5 (1 to 20)

Allergic rhinitis score

 

8 (0 to 18)

Gastroesophageal reflux disease

7 (19.4)

 

Psychiatric disorder

3 (8.3)

 

Smoking in the home (reported by the residents)

12 (33.3)

 

Fully adherent to treatment

2 (5.6)

 

Previous pulmonary function testing

16 (44.4)

 

Incorrect inhaler technique

13 (36)

 

Previous ICU admission

7 (19.5)

 

Uncontrolled asthma (GINA criteria)

36 (100)

 

Posology and medications in use

  

   Equivalent dose of budesonide (μg)

 

800 (800 to 1200)

   ICS alone

9 (25.0)

 

   ICS + LABA

27 (75.0)

 

   Leukotriene receptor antagonists

4 (11.1)

 

   Continuous oral ICS

3 (8.3)

 

   Omalizumab

0 (0.0)

 
  1. IQR: interquartile range; BMI: body mass index; ICU: intensive care unit; GINA: Global Initiative for Asthma.