Skip to main content

Table 1 Clinical characteristics of patients with suspected LIP

From: HIV associated Lymphocytic Interstitial Pneumonia: a clinical, histological and radiographic study from an HIV endemic resource-poor setting

  Definite LIP Non-LIP Probable LIP Definite & probable LIP P value
  n = 13 n = 10 n = 19 n = 32  
Demographic characteristics
Age median (range) 34 (21–57)* 42 (26–66)* 39(20–52) 35 (20–57) *p = 0.11
Gender: Female n (%) 11(85%)* 3 (30%)*# 15 (79%) 20 (77%)# *p = 0.006
#p = 0.008
CD4 count median (range) 194 (104–464)* 157(51–323)* 216 (30–444) 216 (30–464) p = 0.18
Number of participants on ARV at presentation 1/11 (9%) 5/8 (62.5%)* 8/13 (61.5%) 9/24(37.5%)* *p = 0.25
Symptoms
Duration in months Median (range) 5 (1–84) 4 (.75-12) 6 (0.5-24) 6 (0.5-84) p = 0.45
Presence of cough 10/11 (90%) 10/10 (100%) 16/18 (88%) 26/29(89.7%)  
Productive cough 7/11 (64%)* 6/10(60%)* 12/16 (75%) 19/27 (71%) *p = 0.43
Dyspnea (NHYA)      
Class 1 3 (25%) 2 (20%) 6 (33%) 9 (30%)  
Class 2 8 (67%) 4 (40%) 9 (50%) 17 (57%)  
Class 3 1(3%) 3 (30%) 3 (17%) 4 (13%)  
Class 4 0 1 (10%) 0(0%) 0  
Referral diagnosis of non-resolving TB 77% 70% 86%   
Examination findings
BMI kg/cm2 mean (SD) 25.3(5.3) 23.8(6.2) 23.9(5.4) 24.6(5.2) p = 0.94
Presence of clubbing 0/ 11 (0%) 3/10 (30%) 6/18(33%) 6/29 (20%)  
Auscultation  
Normal 4 (33%) 2 (20%) 7 (39%) 11 (38%)  
Bibasilar crackles 7 (58%) 6 (60%) 9 (50%) 16 (55%)  
Diffuse crackles 0 1(10%) 2 (11%) 2 (7%)  
Wheeze 0 0 0 0  
Bronchial breathing 1 (8%) 1(10%) 0 0  
  1. *,#p value for comparison between groups indicated.