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Table 2 Association between irisin and CPET parameters depending on different adjustment sets

From: Association of circulating irisin and cardiopulmonary exercise capacity in healthy volunteers: results of the Study of Health in Pomerania

 

peakVO2

VO2@AT

Oxygen pulse

Maximum power output

 

ß coefficient (Stderr)

p

ß coefficient (Stderr)

p

ß coefficient (Stderr)

p

ß coefficient (Stderr)

p

Whole population

        

Men (n = 322)

        

 adjusted for age, BMI, smoking

−97.43 (43.139)

0.02

−6.388 (26.278)

0.81

−0.463 (0.249)

0.06

−7.656 (3.258)

0.02

 adjusted for age, BMI, smoking, glucose, total cholesterol

−108.2 (43.752)

0.01

−11.48 (26.618)

0.67

−0.544 (0.252)

0.03

−8.434 (3.305)

0.01

Women (n = 418)

        

 adjusted for age, BMI, smoking

27.580 (23.166)

0.23

0.981 (13.347)

0.94

0.054 (0.149)

0.72

−1.296 (1.872)

0.49

 adjusted for age, BMI, smoking, glucose, total cholesterol

25.103 (23.337)

0.28

−0.805 (13.436)

0.95

0.021 (0.150)

0.89

−1.410 (1.887)

0.46

Subpopulation of subjects with a maximal time-lag between blood sampling and pulmonary function testing of one month

Men (n = 177)

        

 adjusted for age, BMI, smoking

−96.07 (58.396)

0.10

4.926 (35.355)

0.89

−0.442 (0.335)

0.19

−8.720 (4.413)

0.05

 adjusted for age, BMI, smoking, glucose, total cholesterol

−116.9 (60.121)

0.05

2.569 (36.563)

0.94

−0.557 (0.342)

0.11

−9.979 (4.557)

0.03

Women (n = 225)

        

 adjusted for age, BMI, smoking

80.507 (27.836)

<.01

24.328 (18.694)

0.19

0.455 (0.177)

0.01

1.839 (2.302)

0.43

 adjusted for age, BMI, smoking, glucose, total cholesterol

80.805 (28.106)

<.01

22.367 (18.856)

0.24

0.446 (0.179)

0.01

1.775 (2.326)

0.45

  1. BMI = body-mass index; peakVO2 = highest 10-second average of VO2 in the last minute of exercise; VO2@AT = VO2 at anaerobic threshold. All models were further adjusted for time between core examination and pulmonary function testing and month of core examination.