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Table 3 Inhalation parameters after enhanced training, and percentage change versus pre-training values

From: Inhalation characteristics of asthma patients, COPD patients and healthy volunteers with the Spiromax® and Turbuhaler® devices: a randomised, cross-over study

  Children with asthma (n = 23) Adolescents with asthma (n = 27) Adults with asthma (n = 50) Adults with COPD (n = 50) Healthy adults (n = 50)
Spiromax
PIF ± SD, L/min 77.99 ± 17.64 83.87 ± 15.12 85.45 ± 14.60 68.08 ± 18.48 98.68 ± 9.25
(Change ± SD, %) (14.18 ± 22.51) (26.34 ± 22.83) (19.31 ± 26.65) (25.27 ± 33.36) (18.93 ± 22.39)
Max ΔP ± SD, kPa 6.25 ± 2.64 7.11 ± 2.50* 7.36 ± 2.33 3.94 ± 2.09 9.62 ± 1.66
(Change ± SD, %) (35.24 ± 59.55) (64.64 ± 60.13) (49.30 ± 74.81) (35.94 ± 81.15) (46.36 ± 58.85)
ACC ± SD, kPa/s 19.10 ± 14.63 26.72 ± 18.42 30.02 ± 25.30* 18.79 ± 17.07* 32.21 ± 17.19
(Change ± SD, %) (102.11 ± 171.24) (189.28 ± 234.48) (247.72 ± 482.94) (152.83 ± 233.91) (212.09 ± 284.44)
Inhalation volume ± SD, L 1.58 ± 0.60 2.13 ± 0.67 2.38 ± 1.12 1.90 ± 0.90 3.07 ± 1.05
(Change ± SD, %) (14.68 ± 42.03) (10.09 ± 21.40) (1.25 ± 26.19) (14.73 ± 59.64) (6.41 ± 27.99)
Turbuhaler
PIF ± SD, L/min 69.46 ± 16.18 74.31 ± 12.94 76.73 ± 15.01 60.09 ± 16.95 90.36 ± 11.00
(Change ± SD, %) (20.03 ± 17.51) (32.68 ± 27.56) (22.17 ± 28.32) (24.06 ± 25.56) (18.16 ± 21.92)
Max ΔP ± SD, kPa 5.70 ± 2.53 6.38 ± 2.21 6.86 ± 2.51 4.37 ± 2.44§ 9.30 ± 2.09
(Change ± SD, %) (50.99 ± 40.47) (83.35 ± 82.04) (57.12 ± 89.53) (60.30 ± 73.15) (44.33 ± 56.21)
ACC ± SD, kPa/s 19.76 ± 12.37 23.58 ± 12.52 25.96 ± 20.29 15.72 ± 13.98 30.12 ± 14.34
(Change ± SD, %) (214.36 ± 295.99) (237.34 ± 365.66) (188.77 ± 271.47) (254.32 ± 426.12) (275.05 ± 389.83)
Inhalation volume ± SD, L 1.29 ± 0.53 1.77 ± 0.56 2.11 ± 0.90 1.66 ± 0.71 2.79 ± 0.96
(Change ± SD, %) (9.58 ± 31.29) (15.52 ± 30.85) (5.88 ± 34.35) (11.26 ± 40.03) (0.69 ± 19.91)
  1. Data shown are mean ± standard deviation *p < 0.05 vs Turbuhaler; p < 0.01 vs Turbuhaler; p < 0.0001 vs Turbuhaler; §p < 0.01 vs Spiromax.