Figure 3
From: Serological assessment of neutrophil elastase activity on elastin during lung ECM remodeling
Degradation of Elastin in IPF and lung cancer. (A): EL-NE fragment levels in serum from patients with IPF (n = 10) compared with controls (n = 9). ** p < 0.01. (B): EL-NE fragment levels in serum from patients diagnosed with lung cancer (n = 40 in total), SCC (n = 16), adenocarcinoma (n = 16) and SCLC (n = 8) compared with controls (n = 12). **** p < 0.0001. Groups were compared by T-test with Welch correction. Data are shown as the geometric mean (95% CI). Abbreviations: IPF, idiopathic pulmonary fibrosis; SCC, squamous cell carcinoma; SCLC, small cell lung carcinoma.