Figure 1

Comparison of cardiorespiratory variables between the group of patients with cystic fibrosis (CFG) (n=64) and the control group (CG) (n=64). Data are presented as the confidence interval of the median. Time points analyzed: (1) baseline (rest), (2) 1–2 min of activity, (3) 3–4 min of activity, (4) 5–6 min of activity, and (5) postexercise. α=0.01 by Bonferroni correction. The Mann–Whitney test was used to compare the CFG and CG, and correlations between the time points in each group were determined using the Friedman test (non-parametric, repeated measures); in cases with a positive p-value, the Wilcoxon signed-rank test was performed. (A) Respiratory rate. There was no difference between the CG and CFG for the time points analyzed. In the cluster analysis for the CFG, time point 1 differed from 2 to 4; time point 2 differed from 1; time points 3 and 4 differed from 1 and 5; and time point 5 differed from 3 and 4 (p≤0.001). In the cluster analysis for the CG, time points 3 and 4 differed from 5, and time point 5 differed from 3 and 4 (p≤0.001). (B) Heart rate. There was no difference between the CG and CFG for the time points analyzed. In the cluster analysis for the CFG, time point 1 differed from 2 to 4; time point 2 differed from 1, 4, and 5; time point 3 differed from 1 and 5; time point 4 differed from 1, 2, and 5; and time point 5 differed from 2 to 4 (p≤0.001). In the cluster analysis for the CG, time point 1 differed from 2 to 5; time point 2 differed from 1, 3, 4, and 5; time points 3 and 4 differed from 1, 2, and 5; and time point 5 differed from 1 to 4 (p≤0.001). (C) Transcutaneous oxygen saturation. There was no difference between the CG and CFG for time points 4 and 5. For the other time points, the CG exhibited higher values (time points 1 and 2, p≤0.001; time point 3, p=0.002). In the group analysis for the CFG, time point 1 differed from 2 and 4; time point 2 differed from 1 and 5; time point 3 differed from 5; time point 4 differed from 1 and 5; and time point 5 differed from 2 to 4 (p≤0.001). In the CG, time point 1 differed from 2 to 5 (p≤0.001).