Table 1 Demographic and clinical characteristics of the participants
Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | |
|---|---|---|---|---|---|
Age at intervention (years) | 43 | 37 | 43 | 45 | 37 |
Sex | Male | Male | Male | Male | Male |
Race | White | White | White | White | Black |
Exposure | Stone carver | Sandblaster | Stone quarry truck driver | Sandblaster | Sandblaster |
Duration of symptoms (years) | 13 | 5 | 3 | 11 | 10 |
Main symptom | Dyspnea on exertion | Progressive dyspnea | Dyspnea on exertion | Dyspnea on exertion | Dyspnea on exertion |
Other lung diseases | No | Tuberculosis in 2004 | Tuberculosis in 1999 | Pneumonia in 2005 | Tuberculosis in 2002 |
Smoking | No | 0.6 pack-years, stopped in 2004 | 8 pack-years, stopped in 1999 | No | No |
Post-BD FEV1 (%) | 55.7 | 48.3 | 62.1 | 64.6 | 62.9 |
Post-BD FVC (%) | 89.3 | 61.9 | 94.7 | 100.1 | 93.7 |
Main CT findings at admission | Irregular opacities, mainly at the UULL, with traction bronchiectasis | Diffuse reticulo-nodular infiltrate | Disseminated small nodules, traction bronchiectasis | Disseminated small nodules, traction bronchiectasis | Disseminated small nodules, traction bronchiectasis |
Date of infusion | 8 Aug 2009 | 27 Aug 2009 | 3 Sep 2009 | 26 Oct 2012 | 4 Feb 2010 |
Last outpatient visit and status | 3 Mar 2015, stable | 3 Dec 2014, stable | 3 Dec 2012, stable | 22 Nov 2014, stable | 22 Aug 2011, active TBa |