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Table 1 Demographic and clinical characteristics of the participants

From: Pilot safety study of intrabronchial instillation of bone marrow-derived mononuclear cells in patients with silicosis

  Patient 1 Patient 2 Patient 3 Patient 4 Patient 5
Age at intervention (years) 43 37 43 45 37
Sex Male Male Male Male Male
Race White White White White Black
Exposure Stone carver Sandblaster Stone quarry truck driver Sandblaster Sandblaster
Duration of symptoms (years) 13 5 3 11 10
Main symptom Dyspnea on exertion Progressive dyspnea Dyspnea on exertion Dyspnea on exertion Dyspnea on exertion
Other lung diseases No Tuberculosis in 2004 Tuberculosis in 1999 Pneumonia in 2005 Tuberculosis in 2002
Smoking No 0.6 pack-years, stopped in 2004 8 pack-years, stopped in 1999 No No
Post-BD FEV1 (%) 55.7 48.3 62.1 64.6 62.9
Post-BD FVC (%) 89.3 61.9 94.7 100.1 93.7
Main CT findings at admission Irregular opacities, mainly at the UULL, with traction bronchiectasis Diffuse reticulo-nodular infiltrate Disseminated small nodules, traction bronchiectasis Disseminated small nodules, traction bronchiectasis Disseminated small nodules, traction bronchiectasis
Date of infusion 8 Aug 2009 27 Aug 2009 3 Sep 2009 26 Oct 2012 4 Feb 2010
Last outpatient visit and status 3 Mar 2015, stable 3 Dec 2014, stable 3 Dec 2012, stable 22 Nov 2014, stable 22 Aug 2011, active TBa
  1. BD Bronchodilator, FEV 1 Forced expiratory volume in 1 s, FCV Forced vital capacity, CT Computed tomography, UULL Upper lobes, TB Tuberculosis
  2. amoved to another state