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Table 4 Histopathological findings

From: Comparative investigation of respiratory tract involvement in granulomatosis with polyangiitis between PR3-ANCA positive and MPO-ANCA positive cases: a retrospective cohort study

 

PR3-ANCA

MPO-ANCA

(N = 9)

(N = 6)

Nasal mucosa biopsy

6

1

 Granuloma of artery/perivascular area

2

-

 Necrotizing vasculitis

1

-

 No siginificant findings

4

1

Lung biopsy

7

4

 Granulomatous inflammation of artery/perivascular area

3

1

 Necrotizing vasculitis

2

0

 Granulomatous inflammation of respiratory tract

3

0

 Vasculitis (without necrosis)*

1

1

 No siginificant findings

4

2

Renal biopsy

3

0

 Granuloma

1

-

 Necrotizing vasculitis/glomerulonephritis

2

-

 Vasulitis/glomerulonephritis (without necrosis)*

1

-

 No siginificant findings

-

-

 Classification for ANCA-associated glomerulonephritis

  

  Cresentic

2

-

  Sclerotic

1

-

  1. The specimens of nasal mucosa, lung, and kidney were histopathologically reviewed according to the items of ACR classification criteria and CHCC classification. *; Meaningful but not diagnostic finding. Glomerulonephritis were classified into the categories of focal, crescentic, mixed, or sclerotic according to the histopathologic classification of ANCA-associated glomerulonephritis proposed by Berden.