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Table 5 Univariate and multivariate regression analyses: radiologic indices of survival (n = 74)

From: Clinical impact of high-attenuation and cystic areas on computed tomography in fibrotic idiopathic interstitial pneumonias

 

Univariate

Multivariate

 

HR

95 % CI

P

HR

95 % CI

P

Quantitative CT indices

      

 HAA% (>-200 HU), %

1.47

(1.13 – 1.83)

< 0.01

1.06

(0.86 – 1.06)

NS

 LAA% (<-960 HU), %

0.97

(0.86 – 1.06)

NS

   

 CA%, %

0.98

(0.75 – 1.16)

NS

   

 MLD, HU

1.01

(1.00 – 1.02)

0.01

   

 SD-LD, HU

1.03

(1.01 – 1.04)

< 0.01

   

 Kurtosis

0.67

(0.51 – 0.86)

< 0.01

0.67

(0.44 – 0.96)

0.03

 Skewness

0.28

(0.11 – 0.65)

< 0.01

   

CT visual scores

      

 GGO score

0.74

(0.35 – 1.40)

NS

   

 Fibrosis score

2.00

(1.20 – 3.39)

0.01

1.06

(0.45 – 2.21)

NS

Definite UIP pattern

2.13

(1.05 – 4.47)

0.04

2.36

(0.84 – 7.60)

NS

  1. HR hazard ratio, CI confidence interval, CT computed tomography, HAA% percentage of lung field occupied by high-attenuation areas, CA% percentage of lung field occupied by cystic areas, MLD mean lung density, HU hounsfield units, SD-LD standard deviation of lung densities, GGO ground-glass opacity, UIP usual interstitial pneumonia