Fig. 4

Fibrotic remodelling changes present in bleomycin-treated segments up 7 weeks post-injury. Panels depict histology of H&E stained sections of lungs segments taken at autopsy. a saline-treated segment. b bleomycin-treated segment, patchy areas of inflammation and fibrosis. Semi-quantitative scoring, shown is graphs (c-e) of the pathology revealed increased fibrosis and inflammation in bleomycin-treated segments at 7 weeks post-treatment, compared to saline treated controls (Graphs c-e.). Significance was determined using paired T-test (Wilcoxin for non-normal data) between treatment groups and unpaired T-tests between time points,***p<0.001