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Table 1 Demographic data for the present and literature cases

From: Outcome of corticosteroid administration in autoimmune pulmonary alveolar proteinosis: a retrospective cohort study

Characteristics Present cases Literature data *
  At start of steroid therapy At the diagnosis At the diagnosis
Subjects n (range) 31 29 # 223
Age, median yrs 66 (9-82) 64 (9-82) 50 (9-89)
Gender n (%)    
 Males 17 (55) 16 (55) 151 (68)
 Females 14 (45) 13 (45) 72 (32)
Clinical symptoms n (%)    
 Asymptomatic 9 (29) 5 (17) 70 (32)
 Symptomatic 22 (71) 24 (83) 150 (68)
 Dyspnea 12 (39) 21 (72) 119 (79)
 Cough 14 (45) 12 (41) 51 (34)
 Sputum 1 (3) 1 (3) 8 (5)
 Other 4 (13) 4 (14) 9 (6)
Smoking habits n (%)    
 Never-smoker 16 (52) 15 (52) 93 (43)
 Current or ex-smoker 15 (48) 14 (48) 124 (57)
Dust exposure n (%)    
 Yes 8 (26) 7 (24) 52 (26)
 No 23 (74) 22 (76) 147 (74)
Complications n (%)    
 None 5 (16) 5 (17) 137 (65)
 Hypertension 11 (35) 11 (38) 18 (9)
 Infection 0 (0) 5 (17) 12 (6)
 Hyperlipidemia 7 (22) 7 (24) 9 (4)
 Diabetes mellitus 5 (16) 8 (28) 8 (4)
 Autoimmune disorders 0 (0) 0 (0) 3 (1)
 Pulmonary fibrosis 2 (6) 1 (3) 3 (1)
  1. *Inoue et al. [8]
  2. #Two cases were excluded from enrolled 31 cases, because steroid therapy were started after diagnosis