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Table 1 Demographic data for the present and literature cases

From: Outcome of corticosteroid administration in autoimmune pulmonary alveolar proteinosis: a retrospective cohort study

Characteristics

Present cases

Literature data *

 

At start of steroid therapy

At the diagnosis

At the diagnosis

Subjects n (range)

31

29 #

223

Age, median yrs

66 (9-82)

64 (9-82)

50 (9-89)

Gender n (%)

   

 Males

17 (55)

16 (55)

151 (68)

 Females

14 (45)

13 (45)

72 (32)

Clinical symptoms n (%)

   

 Asymptomatic

9 (29)

5 (17)

70 (32)

 Symptomatic

22 (71)

24 (83)

150 (68)

 Dyspnea

12 (39)

21 (72)

119 (79)

 Cough

14 (45)

12 (41)

51 (34)

 Sputum

1 (3)

1 (3)

8 (5)

 Other

4 (13)

4 (14)

9 (6)

Smoking habits n (%)

   

 Never-smoker

16 (52)

15 (52)

93 (43)

 Current or ex-smoker

15 (48)

14 (48)

124 (57)

Dust exposure n (%)

   

 Yes

8 (26)

7 (24)

52 (26)

 No

23 (74)

22 (76)

147 (74)

Complications n (%)

   

 None

5 (16)

5 (17)

137 (65)

 Hypertension

11 (35)

11 (38)

18 (9)

 Infection

0 (0)

5 (17)

12 (6)

 Hyperlipidemia

7 (22)

7 (24)

9 (4)

 Diabetes mellitus

5 (16)

8 (28)

8 (4)

 Autoimmune disorders

0 (0)

0 (0)

3 (1)

 Pulmonary fibrosis

2 (6)

1 (3)

3 (1)

  1. *Inoue et al. [8]
  2. #Two cases were excluded from enrolled 31 cases, because steroid therapy were started after diagnosis