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Table 3 Demographic and clinical characteristics of patients in the HS, stable COPD and AECOPD groups

From: Quantitative analysis of pathogens in the lower respiratory tract of patients with chronic obstructive pulmonary disease

 

HS

Stable COPD patients

AECOPD patients

(n = 33)

(n = 34)

(n = 32)

Age (years)

65 ± 8

67 ± 7

69 ± 6

Gender (M/F)

20/13

28/6

27/5

BMI (kg/m2)

23.1 ± 5.1

24.2 ± 4.9

23.8 ± 3.9

Tobacco (pack/year)

-

44.2 ± 25.6

43.7 ± 27.8

FEV1 (L)

3.3 ± 0.3

1.3 ± 0.1**

1.2 ± 0.2**

FEV1 % predicted

103.6 ± 7.3

53.4 ± 8.8**

51.4 ± 9.0**

FVC (L)

4.0 ± 0.2

2.9 ± 0.2*

2.7 ± 0.2*

FVC % predicted

102.7 ± 6.7

81.4 ± 9.3**

79.9 ± 7.4**

FEV1/FVC (%)

82.3 ± 6.1

43.8 ± 4.4**

44.1 ± 7.1**

WBC (x109/L)

5.6 ± 1.2

6.1 ± 1.7

11.4 ± 5.1**##

Neutrophils (%)

64.6 ± 6.7

68.7 ± 7.6*

85.4 ± 6.1**##

CRP (mg/L)

6.7 ± 2.4

16.1 ± 6.7**

85.2 ± 30.4**##

  1. All data are expressed as means ± SEM, except gender. *P < 0.05 and **P < 0.01 vs. the HS group; #P < 0.05 and ##P < 0.01 vs. the stable COPD group; FEV1, Forced expiratory volume in one second; FVC, forced vital capacity; CRP, C-reactive protein; HS, Healthy subjects. The spirometry data in AECOPD patients reflect the baseline data in the stable stage
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BMC Pulmonary Medicine

ISSN: 1471-2466

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