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Table 3 Demographic and clinical characteristics of patients in the HS, stable COPD and AECOPD groups

From: Quantitative analysis of pathogens in the lower respiratory tract of patients with chronic obstructive pulmonary disease

  HS Stable COPD patients AECOPD patients
(n = 33) (n = 34) (n = 32)
Age (years) 65 ± 8 67 ± 7 69 ± 6
Gender (M/F) 20/13 28/6 27/5
BMI (kg/m2) 23.1 ± 5.1 24.2 ± 4.9 23.8 ± 3.9
Tobacco (pack/year) - 44.2 ± 25.6 43.7 ± 27.8
FEV1 (L) 3.3 ± 0.3 1.3 ± 0.1** 1.2 ± 0.2**
FEV1 % predicted 103.6 ± 7.3 53.4 ± 8.8** 51.4 ± 9.0**
FVC (L) 4.0 ± 0.2 2.9 ± 0.2* 2.7 ± 0.2*
FVC % predicted 102.7 ± 6.7 81.4 ± 9.3** 79.9 ± 7.4**
FEV1/FVC (%) 82.3 ± 6.1 43.8 ± 4.4** 44.1 ± 7.1**
WBC (x109/L) 5.6 ± 1.2 6.1 ± 1.7 11.4 ± 5.1**##
Neutrophils (%) 64.6 ± 6.7 68.7 ± 7.6* 85.4 ± 6.1**##
CRP (mg/L) 6.7 ± 2.4 16.1 ± 6.7** 85.2 ± 30.4**##
  1. All data are expressed as means ± SEM, except gender. *P < 0.05 and **P < 0.01 vs. the HS group; #P < 0.05 and ##P < 0.01 vs. the stable COPD group; FEV1, Forced expiratory volume in one second; FVC, forced vital capacity; CRP, C-reactive protein; HS, Healthy subjects. The spirometry data in AECOPD patients reflect the baseline data in the stable stage