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Table 3 Results - clinical course 1 h and 24 h after BAL procedure

From: Clinical course and complications following diagnostic bronchoalveolar lavage in critically ill mechanically ventilated patients

 

Before BAL

1 h after BAL

24 h after BAL

PaO2/FiO2 [kPa]

29 (CI 25–32)

25 (CI 23–29) p < 0.05

31 (CI 27–33)

PaO2/FiO2 [mmHg]

218 (CI 188–240)

189 (CI 173–218)

233 (CI 203–248)

PaO2/FiO2 decreased >25 % baseline [% of patients]

 

29 %

14 %

PEEP mean [cmH2O]

9.4 (CI 9.1–9.8)

9.6 (CI 9.2–9.9)

9.6 (CI 9.2–10)

PEEP increased

 

7 %

15 %

FiO2 mean [%]

52 (CI 49–55)

54 (CI 51–57)

43 (CI 41–46) p < 0.0001

FiO2 increased ≥ 10 % baseline [% of patients]

 

27 %

8 %

pH mean

7.41 (CI 7.40–7.42)

7.40 (CI 7.39–7.41)

7.41 (CI 7.40–7.42)

pCO2 mean [kPa]

5.2 (CI 5.0–5.4)

5.4 (CI 5.2–5.6)

5.2 (CI 5.0–5.4)

pCO2 mean [mmHg]

39 (CI 38–41)

41 (CI 39–42)

39 (CI 38–41)

MAP mean [mmHg]

84 (CI 81–86)

79 (CI 76–81)

83 (CI 81–86)

Heart rate mean [beats/min]

96 (CI 93–100)

94 (CI 93–99)

91 (CI 88–94)

Norepinephrine [% of patients]

58 %

57 %

62 %

Norepinephrine median

0.125

0.109

0.125

1. quartile/3. Quartile [μg/kg/min]

0.050/0.201

0.075/0.202

0.068/0.219

Dobutamine [% of patients]

3 %

3 %

3 %

Dobutamine median

5

5

3

1. quartile/3. Quartile [μg/kg/min]

3/5

2/5

3/5

Hemodynamic instabilitya[% of patients]

 

5 %

7 %

Hemodynamic instabilitya at any time within 24 h [% of patients]

  

22 %

  1. CI 95 % confidence interval, MAP mean arterial pressure, PEEP positive end-expiratory pressure, FiO 2 fraction of inspired oxygen, PaO 2 arterial partial oxygen pressure, SOFA sequential organ failure assessment
  2. adecrease of mean arterial pressure (MAP) < 55 mmHg and/or necessity to initiate norepinephrine > 0.15 μg/kg/min / dubutamine >5 μg/kg/min and/or the necessity to more than double the dose of norepinephrine or dobutamine