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Table 1 Cases of culture confirmed B. pseudomallei infection in CF

From: An international, multicentre evaluation and description of Burkholderia pseudomallei infection in cystic fibrosis

Patient Year isolated Location of acquisition Country of residence Age Gender CFTR Mutation FEV1% BMI Co-pathogens ETOH >40 g daily Diabetes
1 (O’Carroll, 2003) [12] 1987 Northern Australia Australia 21 M F508del/F508del 49 21 Pseud No No
2 Early 1990’s Northern Australia Australia 40 M F508del/R117 44.5 23 Pseud Yes No
Mycobacterium intracellulare
3 (Schülin, 2001) [14] 1992 Likely Thailand Germany 31 M Unknown Unknown Unknown Unknown Unknown Unknown
4 (Visca, 2001) [15] 1998 South-East Asia Italy 25 F Unknown Unknown Unknown Pseud Unknown Unknown
BCp
5 (Dance, 1999) [11] 1998 Malaysia England 20 M Unknown Unknown Unknown Unknown Unknown Unknown
6 (Holland, 2002) [16] 1999 Northern Australia New Zealand 8.5 M G551D/1717-16 > A 46 15 Pseud No No
Aspergillus fumigatus
7 (Holland, 2002) [16] 2000 Northern Australia New Zealand 7 F G551D/1717-16 > A Unknown 19 Haemophilus influenzae No No
Staph A
8 (O’Carroll, 2003) [12] 2000 Northern Australia Australia 21 M F508del/F508del 35 22 Pseud No Yes
Staph A
BCp
9a (Holland, 2002) [16] 2000 Northern Australia Australia 18 M F508del/F508del 45 21 Pseud Yes No
Staph A
BGl
Mycobacterium intracellulare
Other
10 (O’Carroll, 2003) [12] 2001 Northern Australia Australia 14 M F508del/G542X 80 17 Pseud No No
Staph
11 (Holland, 2002) [16] 2001 Northern Australia New Zealand 38 M F508del/F508del 36 19 Pseud No IFG
Staph A
12 (O’Carroll, 2003) [12] 2001 Northern Australia Australia 25 F Unknown 80 20 Pseud No No
Staph A
BCp
13 (Asiah, 2006) [8] 2004 Malaysia Malaysia 17 M Unknown Unknown Unknown Pseud Unknown Unknown
Staph A
14 (Barth, 2007) [9] 2005 Brazil Brazil 17 F Unknown Unknown Unknown Pseud Unknown Unknown
Staph A
15 2005 Thailand England 30 F Unknown 56 21 Pseud No Yes
Staph A
Aspergillus fumigatus
16 (Corral, 2008) [10] 2006 British Virgin Islands England 17 M F508del/E60X 63 22 Pseud Unknown No
Staph A
Canada
17 2007 Northern Australia Australia 38 M F508del/F711 + 5G > A 29 19 Pseud No No
Staph A
Aspergillus terreus
18 2007 Thailand New Zealand 10 F F508del/17aa + IG74 107 16 Pseud No No
Staph A
Other
19 2008 Thailand Australia 22 F F508del/F508del 85 23 Pseud Yes Yes
20 (O’Sullivan, 2011) [13] 2009 Aruba USA 7 F F508del/F508del 88 13 None No No
21 2010 Vietnam/Cambodia England 23 F F508del/F508del 44 19 Pseud No No
Haemophilus influenzae
22 (Radhakrishna, 2014) [17] 2011 Thailand Australia 25 M Unknown 95 24 Pseud Unknown No
Aspergillus fumigatus
23 2012 Malaysia/Philippines Malaysia 19 M R553X/unknown 18 17 Pseud No No
24 2013 Thailand/Japan England 30 M F508del/E60X 67 23 Pseud No No
25 2015 Thailand England 21 F F508del/F508del 71 18 Pseud No No
Staph A
  1. Pseud Pseudomona aeruginosa, Staph A Staphylococcus aureus, BCp Burkholderia cepacia complex, BGl Burkholderia gladioli, IFG impaired fasting glucos
  2. a3 distinct B. pseudomallei infections were recorded in this patient over 8 years