Table 2 The mean serum concentrations of examined cytokines in patients with IPF and sarcoidosis
|  | Sarcoidosis n = 43 | IPF n = 17 | Control group n = 20 |
|---|---|---|---|
|  | Mean ± SEM | Mean ± SEM | Mean ± SEM |
| Â | Median (95Â % CI) | Median (95Â % CI) | Median (95Â % CI) |
Angiopoeitin-2 | 221.5 ± 28.7 | 251.6 ± 45.6 | 288.8 ± 68,9762 |
(pg/ml) | 173.5 (120.7–301.8) | 237.8 (72.1–294.6) | 168.7 (95.6–360.4) |
Follistatin | 357.6 ± 31.9 | 582.5 ± 64.5** | 462.7 ± 89.6 |
(pg/ml) | 346.5 (264.7–416.1) | 545.8 (418.5–674.5) | 291.2 (231.5–478.3) |
GM-CSF | 31.7 ± 4.7 | 67.6 ± 6.4*** | 29.5 ± 5.2 |
(pg/ml) | 15.7 (10.5–43.1) | 71.1 (41.7–86.5) | 24.8 (9.3–48.2) |
IL-8 | 30.8 ± 4.0 | 76.3 ± 5.2*** | 28.9 ± 4.7 |
(pg/ml) | 15.8 (13.8–39.7) | 79.9 (57.9–96.3) | 20.7 (11.4–46.0) |
PDGF-BB | 5528.3 ± 551.2 | 8629.8 ± 869.1# | 7080.1 ± 1046.6 |
(pg/ml) | 4607.0 (3464.6–6128.8) | 7178.0 (6732.8–9948.4) | 5384.1 (3173.5–10040.3) |
PECAM-1 | 2490.4 ± 232.9 | 3392.1 ± 376.8* | 2316.9 ± 388.9 |
(pg/ml) | 2290.7 (1693.7–2795.2) | 3147.5 (2428.6–4072.6) | 1798.1 (1226.1–2563,1) |
VEGF | 88.7 ± 7.7 | 120.5 ± 16.0 | 78.0 ± 10.8 |
(pg/ml) | 84.1 (61.9–95.4) | 94.3 (77.6–157.2) | 80.1 (32.6–109.2) |