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Table 1 Patient Demographics as a function of chronic infection with epidemic P. aeruginosa strains

From: Infection control knowledge, beliefs and behaviours amongst cystic fibrosis patients with epidemic Pseudomonas aeruginosa

Category Epidemic P. aeruginosa (n = 30) Cohort with unique chronic P. aeruginosa infection Entire CF cohort without epidemic P. aeruginosa
UNI (n = 67) P Value ENT (n = 112) P Value
Age 32.81 (IQR 29.5–39.3) 29.61 (IQR 24.9–41.9) 0.13 29.5 (IQR 23.7–42.5) 0.10
Gender (Female) 17 (56.7 %) 40 (60 %) 0.48 60 (53.4 %) 0.84
Pancreatic Sufficient 1 (3.3 %) 6 (9 %) 0.3 19 (17 %) 0.07
F508 del Homozygous 18 (60 %) 37 (56 %) 0.44 56 (50 %) 0.42
≥1 F508del allele 27 (90 %) 57 (66 %) 0.5 93 (83 %) 0.56
Status post lung transplant 12 (40 %) 9 (13.4 %) 0.005 12 (10.7 %) <0.001
Age at transplant 29 (IQR 24.5–31.2) 33.27 (IQR 23.4–35.7) 0.53 33.9 (IQR 23.3–38.3) 0.41
Chronic Infection Status
P. aeruginosa 30 (100 %) 67 (100 %) N/A 67 (59.8 %) <0.001
S. aureus (MSSA) 5 (20 %) 29 (43.7) 0.009 61 (54.5 %) <0.001
 MSSA as sole pathogen 0 0 N/A 21 (18.8 %) 0.007
S. aureus (MRSA) 1 (3 %) 3 (5 %) 0.63 8 (7 %) 0.68
S. maltophilia 0 0 N/A 2 (2 %) 1
 Non-tuberculous mycobacteria 0 6 (9 %) 0.1 17 (15.1 %) 0.02
M. abscessus complexa 0 2 (3 %) 0.48 10 (9 %) 0.12
M. avium complex 0 4 (6 %) 0.22 7 (6 %) 0.34
A. xylosoxidans 0 0 N/A 2 (2 %) 1
B. cepacia complex (Bcc)b 1 (3 %) 2 (3 %) 0.67 4 (3.5 %) 1
Aspergillus fumigatus 2 (6.6 %) 2 (3 %) 0.36 5 (4.5 %) 0.64
 No chronic pathogens 0 0 N/A 6 (5.3 %) 0.34
  1. a M. abscessus complex = 8 M. abscessus abscessus, 2 M. abscessus bolletti
  2. bBcc = B. multivorans 1, B. cenocepacia 3