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Table 1 Demographic and clinical characteristics of study population

From: p-STAT6, PU.1, and NF-κB are involved in allergen-induced late-phase airway inflammation in asthma patients

Characteristics Allergic asthma patients n = 19 Healthy subjects n = 14
Age, median (range), years 25 (18–36) 27 (20–35)
Sex (male/female), n 10/9 7/6
Wheal diameter induced by allergen, median (range), mm 6.8 (5–11)
Sensitization to D. pteronyssinus/ birch/5 grass mixture allergen, n 12/4/3
PD20, geometric mean (range), mg 0.13 (0.03–0.42)
FEV1, mean ± SD (range), % of predicted 97 ± 10 (82–118) 102 ± 8 (95–122)
Maximum fall in FEV1 after bronchial allergen challenge during the first hour, median (range), % 27 (22–34)* 2 (3–8)
  1. FEV1, forced expiratory volume in the first second
  2. PD20, provocative dose of methacholine causing a 20 % fall in FEV1
  3. *P < 0.05 versus healthy individuals