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Table 1 Demographic and clinical characteristics of study population

From: p-STAT6, PU.1, and NF-κB are involved in allergen-induced late-phase airway inflammation in asthma patients

Characteristics

Allergic asthma patients n = 19

Healthy subjects n = 14

Age, median (range), years

25 (18–36)

27 (20–35)

Sex (male/female), n

10/9

7/6

Wheal diameter induced by allergen, median (range), mm

6.8 (5–11)

Sensitization to D. pteronyssinus/ birch/5 grass mixture allergen, n

12/4/3

PD20, geometric mean (range), mg

0.13 (0.03–0.42)

FEV1, mean ± SD (range), % of predicted

97 ± 10 (82–118)

102 ± 8 (95–122)

Maximum fall in FEV1 after bronchial allergen challenge during the first hour, median (range), %

27 (22–34)*

2 (3–8)

  1. FEV1, forced expiratory volume in the first second
  2. PD20, provocative dose of methacholine causing a 20 % fall in FEV1
  3. *P < 0.05 versus healthy individuals