Prognosis of nonspecific interstitial pneumonia correlates with perivascular CD4+ T lymphocyte infiltration of the lung

Table 4 Distribution of T lymphocytes in patients with different histological patterns

Tissue	Cellular NSIP (n = 22)	Mixed NSIP (n = 28)	fibrotic NSIP (n = 5)	p value
CD4+ T lymphocytes (number/0.1 mm²)
Follicle region	163.37 ± 89.58	159.69 ± 94.36	161.93 ± 68.14	0.990
Perivascular region	78.12 ± 34.79	49.74 ± 22.42	53.10 ± 18.17	0.003*
Interstitial region	40.85 ± 12.66	39.54 ± 11.52	38.48 ± 13.97	0.894
Peribronchial region	27.53 ± 15.60	25.70 ± 13.82	20.10 ± 8.84	0.575
CD8+ T lymphocytes (number/0.1 mm²)
Follicle region	123.11 ± 77.81	72.62 ± 26.37	110.74 ± 36.94	0.006
Perivascular region	57.51 ± 23.43	38.91 ± 17.50	52.60 ± 29.89	0.011
Interstitial region	57.96 ± 39.81	36.26 ± 17.53	43.83 ± 18.69	0.037
Peribronchial region	39.11 ± 22.52	27.80 ± 16.27	29.40 ± 12.50	0.111

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