From: Bronchiectasis diagnosed after renal transplantation: a retrospective multicenter study
Variables | Total (n = 46) |
---|---|
Serum creatinine (μmol/L) | 155.9 ± 83.5 [63.0–602.0] |
Creatinine clearance (mL/min, MDRD formula) | 46.4 ± 25.6 [17.0–173.0] |
Lymphocytes (/mm3) (n = 36) | 1295 ± 717 [19–3200] |
B Lymphocytes (n = 19) | 182 ± 296 [1–1194] |
T Lymphocytes (n = 19) | 781 ± 646 [17–2029] |
CD4+ T Lymphocytes (n = 19) | 562 ± 446 [9–1786] |
CD8+ T Lymphocytes (n = 19) | 352 ± 296 [8–1287] |
Electrophoresis (n = 21) | |
Gammaglobulins (g/L) | 8.0 ± 2.7 [4.0–14.0] |
Immunoglobulin assays (n = 18) | |
IgG (g/L) | 8.2 ± 3.2 [3.2–15.5] |
IgG1 (g/L) (n = 8) | 5.6 ± 3.4 [0–11.1] |
IgG2 (g/L) (n = 8) | 2.0 ± 1.3 [0–4.1] |
IgG3 (g/L) (n = 8) | 0.3 ± 0.1 [0–0.5] |
IgG4 (g/L) (n = 8) | 0.2 ± 0.3 [0–0.8] |
IgA (g/L) | 1.4 ± 0.8 [0.2–3.5] |
IgM (g/L) | 0.6 ± 0.4 [0.1–1.4] |
Hypogammaglobulinemiaa | 15 (46.9) |
MPA treatment at time of diagnosis | 42 (91.3) |
MPA daily dose (g) (n = 41) | 1.5 ± 0.6 [0.5–3.5] |
MPA area under the curve (n = 21, mg.h/L) | 42.1 ± 15.4 [20.5–80.0] |
Spirometry (n = 22) | |
Obstructive disorder | 8 (36.4) |
Microbiological data (n = 34) | |
Sputum | 4 |
Fiberoptic Bronchoscopy | 30 |
Positive microbiological findings | 22 (64.7) |
Haemophilus influenzae | 12 |
Streptococcus species | 3 |
Pseudomonas aeruginosa | 5 |
Methicillin-resistant Staphylococcus aureus | 1 |
Aspergillus fumigatus | 2 |
Other bacteria | 4 |