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Table 4 Laboratory, Microbiology, Spirometry Data at the time of the Diagnosis of Bronchiectasis

From: Bronchiectasis diagnosed after renal transplantation: a retrospective multicenter study

Variables Total (n = 46)
Serum creatinine (μmol/L) 155.9 ± 83.5 [63.0–602.0]
 Creatinine clearance (mL/min, MDRD formula) 46.4 ± 25.6 [17.0–173.0]
Lymphocytes (/mm3) (n = 36) 1295 ± 717 [19–3200]
 B Lymphocytes (n = 19) 182 ± 296 [1–1194]
 T Lymphocytes (n = 19) 781 ± 646 [17–2029]
 CD4+ T Lymphocytes (n = 19) 562 ± 446 [9–1786]
 CD8+ T Lymphocytes (n = 19) 352 ± 296 [8–1287]
Electrophoresis (n = 21)  
 Gammaglobulins (g/L) 8.0 ± 2.7 [4.0–14.0]
Immunoglobulin assays (n = 18)  
 IgG (g/L) 8.2 ± 3.2 [3.2–15.5]
 IgG1 (g/L) (n = 8) 5.6 ± 3.4 [0–11.1]
 IgG2 (g/L) (n = 8) 2.0 ± 1.3 [0–4.1]
 IgG3 (g/L) (n = 8) 0.3 ± 0.1 [0–0.5]
 IgG4 (g/L) (n = 8) 0.2 ± 0.3 [0–0.8]
 IgA (g/L) 1.4 ± 0.8 [0.2–3.5]
 IgM (g/L) 0.6 ± 0.4 [0.1–1.4]
Hypogammaglobulinemiaa 15 (46.9)
MPA treatment at time of diagnosis 42 (91.3)
 MPA daily dose (g) (n = 41) 1.5 ± 0.6 [0.5–3.5]
 MPA area under the curve (n = 21, mg.h/L) 42.1 ± 15.4 [20.5–80.0]
Spirometry (n = 22)  
 Obstructive disorder 8 (36.4)
Microbiological data (n = 34)  
 Sputum 4
 Fiberoptic Bronchoscopy 30
 Positive microbiological findings 22 (64.7)
  Haemophilus influenzae 12
  Streptococcus species 3
  Pseudomonas aeruginosa 5
  Methicillin-resistant Staphylococcus aureus 1
  Aspergillus fumigatus 2
  Other bacteria 4
  1. Data are expressed as frequency (percentage) or mean ± standard deviation [minimum, maximum]
  2. aDefined as gammaglobulins less than 9 g/dL and/or IgG less than 7 g/L, and available for 32 patients either by electrophoresis and/or immunoglobulin assay