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Table 4 Laboratory, Microbiology, Spirometry Data at the time of the Diagnosis of Bronchiectasis

From: Bronchiectasis diagnosed after renal transplantation: a retrospective multicenter study

Variables

Total (n = 46)

Serum creatinine (μmol/L)

155.9 ± 83.5 [63.0–602.0]

 Creatinine clearance (mL/min, MDRD formula)

46.4 ± 25.6 [17.0–173.0]

Lymphocytes (/mm3) (n = 36)

1295 ± 717 [19–3200]

 B Lymphocytes (n = 19)

182 ± 296 [1–1194]

 T Lymphocytes (n = 19)

781 ± 646 [17–2029]

 CD4+ T Lymphocytes (n = 19)

562 ± 446 [9–1786]

 CD8+ T Lymphocytes (n = 19)

352 ± 296 [8–1287]

Electrophoresis (n = 21)

 

 Gammaglobulins (g/L)

8.0 ± 2.7 [4.0–14.0]

Immunoglobulin assays (n = 18)

 

 IgG (g/L)

8.2 ± 3.2 [3.2–15.5]

 IgG1 (g/L) (n = 8)

5.6 ± 3.4 [0–11.1]

 IgG2 (g/L) (n = 8)

2.0 ± 1.3 [0–4.1]

 IgG3 (g/L) (n = 8)

0.3 ± 0.1 [0–0.5]

 IgG4 (g/L) (n = 8)

0.2 ± 0.3 [0–0.8]

 IgA (g/L)

1.4 ± 0.8 [0.2–3.5]

 IgM (g/L)

0.6 ± 0.4 [0.1–1.4]

Hypogammaglobulinemiaa

15 (46.9)

MPA treatment at time of diagnosis

42 (91.3)

 MPA daily dose (g) (n = 41)

1.5 ± 0.6 [0.5–3.5]

 MPA area under the curve (n = 21, mg.h/L)

42.1 ± 15.4 [20.5–80.0]

Spirometry (n = 22)

 

 Obstructive disorder

8 (36.4)

Microbiological data (n = 34)

 

 Sputum

4

 Fiberoptic Bronchoscopy

30

 Positive microbiological findings

22 (64.7)

  Haemophilus influenzae

12

  Streptococcus species

3

  Pseudomonas aeruginosa

5

  Methicillin-resistant Staphylococcus aureus

1

  Aspergillus fumigatus

2

  Other bacteria

4

  1. Data are expressed as frequency (percentage) or mean ± standard deviation [minimum, maximum]
  2. aDefined as gammaglobulins less than 9 g/dL and/or IgG less than 7 g/L, and available for 32 patients either by electrophoresis and/or immunoglobulin assay