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Table 1 Baseline characteristics of study patients

From: Performance of noninvasive ventilation in acute respiratory failure in critically ill patients: a prospective, observational, cohort study

Characteristics NIV failure 26 (30.6 %) NIV success 59 (69.4 %) P value
Age (years) 67 (21) 77 (14) 0.031a
Male gender, n° (%) 17 (65.4) 27 (45.8) 0.106b
Mean arterial pressure (mmHg) 81 (24) 93 (21) 0.032a
Heart rate (beats/min) 107 (25) 95 (19) 0.031a
APACHE II score 16.0 (4.7) 13.4 (5.3) 0.034a
Arterial pH 7.36 (0.08) 7.39 (0.07) 0.106a
Bicarbonate (mmol/L) 19.6 (7.3) 23.7 (4.7) 0.005a
PaCO2 (mmHg), median [IQR] 30.8 [26.6–40.1] 35.3 [31.5–43.5] 0.032c
PaCO2 ≥ 45 mmHg, n° (%) 7 (26.9) 21 (35.6) 0.466b
PaO2/FiO2 277 (148) 282 (109) 0.878a
Arterial lactate (mg/dl), median [IQR] 17 [14–26] 12 [8–21] 0.046c
Hemoglobin (mg/dl) 10.6 (2.1) 11.0 (2.1) 0.499a
Reason for ICU admission, n° (%)    
Medical 20 (76.9) 53 (89.8) 0.174b
Operative 6 (23.1) 6 (10.2)  
Comorbidities, n (%)    
Diabetes Mellitus 9 (34.6) 15 (25.4) 0.438b
Transplantation 7 (26.9) 2 (3.4) 0.003b
Chronic renal failure 6 (23.1) 8 (13.6) 0.344b
Systemic hypertension 6 (23.1) 17 (28.8) 0.792b
COPD 6 (23.1) 12 (20.3) 0.779b
Liver cirrhosis 4 (15.4) 1 (1.7) 0.029b
Coronary insufficiency 4 (15.4) 12 (20.3) 0.766b
Congestive heart failure 4 (15.4) 22 (37.3) 0.072b
Neoplasm 3 (11.5) 7 (11.9) 1.000b
None 2 (7.7) 12 (20.3) 0.209b
  1. Values are mean (SD) or median [IQR] when indicated
  2. ¶ = p values and the respective statistical tests comparing NIV failure vs. NIV success groups. a = Independent t-test, b = Fisher’s exact test, c = Mann–Whitney U test. APACHE II Acute physiology and chronic health evaluation II (The score can range from 0 to 71, with higher scores indicating more severe illness), PaCO 2 Partial pressure of arterial carbon dioxide, and PaO 2 /FiO 2 Ratio of the arterial oxygen partial pressure to the fraction of inspired oxygen, ICU Intensive care unit, COPD Chronic obstructive pulmonary disease