Fig. 1

Chronological changes in serum KL-6 and SP-D. a Serum KL-6 levels at first visit and after 1–4 weeks’ treatment initiation in each patient of the anti-MDA-5 antibody positive (left) and negative groups (right). b Serum SP-D levels at first visit and after 1–4 weeks’ treatment initiation in each patient of the anti-MDA-5 antibody positive (left) and negative groups (right). Abbreviations: KL-6, Krebs von den Lungen-6; SP-D, surfactant protein D; MDA-5, anti-melanoma differentiation-associated gene 5