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Table 1 Summary of clinical characteristics

From: Interstitial lung disease in clinically amyopathic dermatomyositis with and without anti-MDA-5 antibody: to lump or split?

 

MDA-5 positive

MDA-5 negative

p value

(n = 10)

(n = 6)

Gender (male/female)

6/4

2/4

0.608

Age

63.0 (58.0–64.8)

71.5 (64.8–73.8)

0.0913

Smoking history

5 (50 %)

2 (33 %)

0.633

Days from onset to first visit

15.5 (11.0–29.8)

51.0 (39.5–77.5)

0.157

Department of the first visit

 Respiratory medicine

6 (60 %)

1 (17 %)

 Rheumatology

2 (20 %)

5 (83 %)

 Dermatology

2 (20 %)

0

Symptoms and signs at the time of diagnosis

 Gottron’s sign/papule

7 (70 %)

5 (83 %)

1.00

 Heliotrope eruption

7 (70 %)

1 (17 %)

0.119

 V/shawl neck sign

5 (50 %)

2 (33 %)

0.633

 Mechanic’s hands

2 (20 %)

2 (33 %)

0.604

 Palmar erythema

2 (20 %)

1 (17 %)

1.00

 Myalgia

3 (30 %)

0

0.250

 Dry cough

5 (50 %)

4 (67 %)

0.633

 Dyspnea on exertion

5 (50 %)

5 (83 %)

0.307

 Fever

9 (90 %)

3 (50 %)

0.118

  1. Categorical data are presented as numbers (percentages) and were analyzed using Fisher’s exact test. Continuous data are presented as medians (interquartile ranges) and were analyzed using the Mann–Whitney U test. A p value of <0.05 was considered statistically significant
  2. Abbreviation: MDA-5, anti-melanoma differentiation-associated gene 5