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Table 1 Summary of clinical characteristics

From: Interstitial lung disease in clinically amyopathic dermatomyositis with and without anti-MDA-5 antibody: to lump or split?

  MDA-5 positive MDA-5 negative p value
(n = 10) (n = 6)
Gender (male/female) 6/4 2/4 0.608
Age 63.0 (58.0–64.8) 71.5 (64.8–73.8) 0.0913
Smoking history 5 (50 %) 2 (33 %) 0.633
Days from onset to first visit 15.5 (11.0–29.8) 51.0 (39.5–77.5) 0.157
Department of the first visit
 Respiratory medicine 6 (60 %) 1 (17 %)
 Rheumatology 2 (20 %) 5 (83 %)
 Dermatology 2 (20 %) 0
Symptoms and signs at the time of diagnosis
 Gottron’s sign/papule 7 (70 %) 5 (83 %) 1.00
 Heliotrope eruption 7 (70 %) 1 (17 %) 0.119
 V/shawl neck sign 5 (50 %) 2 (33 %) 0.633
 Mechanic’s hands 2 (20 %) 2 (33 %) 0.604
 Palmar erythema 2 (20 %) 1 (17 %) 1.00
 Myalgia 3 (30 %) 0 0.250
 Dry cough 5 (50 %) 4 (67 %) 0.633
 Dyspnea on exertion 5 (50 %) 5 (83 %) 0.307
 Fever 9 (90 %) 3 (50 %) 0.118
  1. Categorical data are presented as numbers (percentages) and were analyzed using Fisher’s exact test. Continuous data are presented as medians (interquartile ranges) and were analyzed using the Mann–Whitney U test. A p value of <0.05 was considered statistically significant
  2. Abbreviation: MDA-5, anti-melanoma differentiation-associated gene 5