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Table 3 Comparison of HRCT findings between patients with and without anti-CADM-antibody

From: Interstitial lung disease in clinically amyopathic dermatomyositis with and without anti-MDA-5 antibody: to lump or split?

 

MDA-5 positive

MDA-5 negative

p value

(n = 10)

(n = 6)

Distribution

 Upper lobe dominant

1 (10 %)

0

1.00

 Lower lobe dominant

9 (90 %)

6 (100 %)

1.00

 Peribronchovascular

2 (20 %)

4 (67 %)

0.118

 Subpleural

8 (80 %)

2 (33 %)

0.118

Main findings

 Consolidation

1 (10 %)

5 (83 %)

0.00762

 Ground glass opacity

5 (50 %)

0

0.0934

 Reticulation

1 (10 %)

0

1.00

 Irregular linear opacity

3 (30 %)

1 (17 %)

1.00

Additional findings

 Traction bronchiectasis

5 (50 %)

4 (67 %)

0.633

 Cyst

0

1 (17 %)

0.375

 Subpleural curve linear shadow

4 (40 %)

3 (50 %)

1.00

 Thickening of interlobular septa

2 (20 %)

2 (33 %)

0.604

 Emphysema

1 (10 %)

1 (17 %)

1.00

 Volume loss

9 (90 %)

5 (83 %)

1.00

  1. Categorical data are presented as numbers (percentages) and were analyzed using Fisher’s exact test
  2. Abbreviations: CADM clinically amyopathic dermatomyositis, HRCT high-resolution computed tomography, MDA-5, anti-melanoma differentiation-associated gene 5