Table 10 Healthcare resource utilization outcomes in the subsequent period
By lung-function change category (based on relative change in FVC%)a | ||||
|---|---|---|---|---|
All Patients | Stable or Marginal (Δ < 10 %) [A] | Significant (Δ ≥ 10 %) [B] | Relative Effect Measure (95 % CI) | |
(N = 490) | (N = 348) | (N = 142) | [B] vs. [A] | |
Subsequent Period | ||||
12-Month IR per Patient | IRR | |||
Rate of IPF-related outpatient visits | 2.39 | 2.34 | 2.56 | 1.09 (0.91–1.32) |
Unscheduled and/or urgent care | 0.30 | 0.24 | 0.55 | 2.25 (1.45–3.50) |
For a suspected AEx | 0.30 | 0.24 | 0.54 | 2.28 (1.47–3.51) |
Rate of outpatient visits indicating that the following medications/treatments were prescribed for IPF | ||||
Prednisone | 1.22 | 1.09 | 1.60 | 1.47 (1.16–1.85) |
Azathioprine | 0.39 | 0.34 | 0.54 | 1.57 (0.96–2.57) |
N-acetylcysteine | 0.70 | 0.67 | 0.79 | 1.19 (0.85–1.67) |
Rate of outpatient visits that included the following tests/procedures | ||||
Arterial blood gas test | 0.25 | 0.19 | 0.35 | 1.80 (0.90–3.60) |
High-resolution computed tomography | 0.29 | 0.27 | 0.36 | 1.32 (0.75–2.33) |
Chest X-ray | 0.55 | 0.54 | 0.60 | 1.11 (0.77–1.59) |
Lung biopsy | 0.03 | 0.03 | 0.01 | 0.39 (0.05–3.44) |
Pulmonary rehabilitation | 0.21 | 0.19 | 0.26 | 1.40 (0.86–2.27) |
Rate of IPF-related ER visits | 0.43 | 0.41 | 0.53 | 1.30 (0.80–2.12) |
For a suspected AEx | 0.19 | 0.16 | 0.29 | 1.84 (1.04–3.27) |
Rate of ER visits that included the following tests/procedures | ||||
Arterial blood gas test | 0.24 | 0.21 | 0.34 | 1.63 (0.95–2.81) |
High-resolution computed tomography | 0.14 | 0.12 | 0.20 | 1.71 (0.88–3.30) |
Chest X-ray | 0.24 | 0.22 | 0.30 | 1.36 (0.79–2.32) |
Supplemental oxygen therapy | 0.21 | 0.18 | 0.29 | 1.58 (0.89–2.79) |
Rate of IFP-related hospitalizations | 0.34 | 0.26 | 0.61 | 2.31 (1.10–4.85) |
For a suspected AEx | 0.20 | 0.13 | 0.43 | 3.46 (2.00–5.98) |
Rate of hospital days not for a suspected AEx | 0.53 | 0.44 | 0.81 | 1.84 (0.38–9.07) |
Rate of hospital days for a suspected AEx | 2.06 | 1.07 | 4.50 | 4.19 (1.69–10.41) |
Rate of ICU stays | 0.13 | 0.09 | 0.28 | 3.07 (1.38–6.83) |
Rate of ICU days | 0.62 | 0.42 | 1.22 | 2.92 (1.12–7.63) |
Rate of hospitalizations that included the following tests/procedures | ||||
Arterial blood gas test | 0.18 | 0.12 | 0.36 | 2.87 (1.48–5.54) |
Mechanical ventilation | 0.08 | 0.07 | 0.16 | 2.47 (0.85–7.12) |
Non-invasive ventilation | 0.08 | 0.04 | 0.20 | 5.50 (2.90–10.45) |
Supplemental oxygen therapy | 0.13 | 0.09 | 0.28 | 3.22 (1.69–6.17) |