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Fig. 4 | BMC Pulmonary Medicine

Fig. 4

From: Survival with sildenafil and inhaled iloprost in a cohort with pulmonary hypertension: an observational study

Fig. 4

Changes in haemodynamic parameters and 6-minute-walk distance over the study (intra-individual responses). (ac) Pulmonary arterial pressure (PAP), (df) cardiac output, (gi) pulmonary vascular resistance (PVR), and (jl) 6-minute-walk distance (6MWD). Data are presented as means ± 95 % confidence interval. Patients were treated with iloprost followed by addition of sildenafil (iloprost/sildenafil), sildenafil followed by addition of iloprost (sildenafil/iloprost), or upfront combination therapy with iloprost and sildenafil (iloprost + sildenafil). Values are shown pre-treatment (baseline), 3 months after therapy initiation (monotherapy), before combination therapy (post-monotherapy baseline), and 3 months after starting combination therapy (combined therapy). *P < 0.05; **P < 0.01; ***P < 0.001. Statistical analysis was conducted using the paired sample t-test (two-tailed)

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