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Table 2 Comparison of patient characteristics between hospitalisations for lower respiratory tract infection with and without acute kidney injury

From: Diagnosis of acute kidney injury and its association with in-hospital mortality in patients with infective exacerbations of bronchiectasis: cohort study from a UK nationwide database

 

Hospitalisations with

AKI diagnosis (N = 230)

(%)

Hospitalisations without AKI diagnosis (N = 7574)

(%)

P Value

Age (years)

  

< 0.001

 < 65

10.9

31.4

 

 65-74

22.2

29.2

 

 75-84

41.7

27.9

 

 ≥ 85

25.2

11.5

 

Sex (Male)

53.0

36.3

< 0.001

Smoking history

  

0.037

 Non-smoker

28.7

37.7

 

 Ex-smoker

59.6

53.4

 

 Current smoker

11.3

8.6

 

 Missing

0.4

0.3

 

Co-diagnosis of COPD

60.4

50.0

0.002

Outpatient eGFR (mL/min/1.73 m2)

  

<0.001

 > 60

33.0

53.8

 

 45-60

17.4

11.0

 

 30-45

21.3

4.2

 

 15-30

10.0

1.3

 

 No measurement

18.3

29.8

 

History of AKI

20.4

4.4

< 0.001

Chronic conditions

   

 Heart failure

19.6

9.0

< 0.001

 Cirrhosis

0.9

0.6

0.638

 Diabetes

26.1

13.1

< 0.001

 Dementia

4.8

2.9

0.107

 Prostatic hypertrophy

17.0

7.5

< 0.001

Drugs with nephrotoxic potential

   

 NSAIDs

28.3

22.5

0.038

 Aminoglycoside nebuliser

1.3

0.1

0.001

 Aminoglycoside injection

1.3

0.7

0.227

 ACEI or ARBs

35.2

21.9

< 0.001

 Diuretics

44.8

29.5

< 0.001

Sepsis diagnosis

12.2

1.0

< 0.001

  1. ACEI, angiotensin converting enzyme inhibitor; AKI, acute kidney injury; ARB, angiotensin II receptor blocker; COPD, chronic obstructive pulmonary disease; eGFR, estimated glomerular filtration rate; NSAIDs, non-steroidal anti-inflammatory drugs