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Table 4 Association between diagnosis of acute kidney injury and in-hospital mortality: main analysis and sensitivity analyses

From: Diagnosis of acute kidney injury and its association with in-hospital mortality in patients with infective exacerbations of bronchiectasis: cohort study from a UK nationwide database

 

In-hospital mortality

Odds ratio (95 % CI) of AKI diagnosis for in-hospital mortality

Hospitalisations with AKI

Hospitalisations without AKI

adjusted by age and sex

adjusted by all the confounding factorsa

Main analysis (N = 7804)

33.0 % (76/230)

6.8 % (516/7,574)

6.72 (4.45-10.15)

5.52 (3.62-8.42)

Sensitivity analysis

    

(i) Excluding patients with no outpatient creatinine measurement (N = 5506)

31.9 % (60/188)

7.9 % (420/5318)

5.83 (3.71 – 9.15)

4.61 (2.90 – 7.33)

(ii) Excluding patients with co-diagnosis of COPD (N = 3882)

29.7 % (27/91)

6.4 % (244/3791)

5.14 (2.59 – 10.21)

4.24 (2.12 – 8.47)

(iii) Hospitalisations limited to pneumonia diagnosis among LRTI (N = 2400)

43.1 % (66/153)

17.5 % (392/2247)

4.13 (2.63 – 6.46)

3.72 (2.34 – 5.89)

  1. AKI, acute kidney injury; COPD, chronic obstructive pulmonary disease; CI, confidence interval; LRTI, lower respiratory tract infection
  2. aAll the factors shown in Table 2, in addition to financial year of hospitalisation