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Table 2 Frequency and effect factors of acquired drug resistant TB emergence at varied time points during SCC

From: Later emergence of acquired drug resistance and its effect on treatment outcome in patients treated with Standard Short-Course Chemotherapy for tuberculosis

Variable

Month1(1) n = 35 (%)

Month2(2) n = 17 (%)

Month3-5(3) n = 10 (%)

Univariate analysis (3) vs (1 + 2)

Multivariate logistic regression (3) vs (1 + 2)

    

P value

OR(95 % CI)

P value

Treatment history

   

0.027*

  

 New

32 (91.4)

12 (70.6)

5 (50.0)

   

 Previously treated

3 (8.6)

5 (29.4)

5 (50.0)

   

No. of drugs to which isolate is resistant

   

0.015*

  

 1

21(60)

6(35.3)

2(20.0)

   

 2

9(25.7)

3(17.6)

1(10.0)

   

 3

4(11.4)

5(29.5)

5(50.0)

   

 4

1(2.9)

3(17.6)

2(20.0)

   

Drug resistance patterns

   

0.003*

  

 Non-MDR-TB

30 (85.7)

12 (70.6)

3 (30.0)

 

Reference

 

 MDR-TB

5 (14.3)

5 (29.4)

7 (70.0)

 

8.3(1.7–39.9)

0.008

  1. * P value was determined by Fisher’s Exact Test