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Table 2 Frequency and effect factors of acquired drug resistant TB emergence at varied time points during SCC

From: Later emergence of acquired drug resistance and its effect on treatment outcome in patients treated with Standard Short-Course Chemotherapy for tuberculosis

Variable Month1(1) n = 35 (%) Month2(2) n = 17 (%) Month3-5(3) n = 10 (%) Univariate analysis (3) vs (1 + 2) Multivariate logistic regression (3) vs (1 + 2)
     P value OR(95 % CI) P value
Treatment history     0.027*   
 New 32 (91.4) 12 (70.6) 5 (50.0)    
 Previously treated 3 (8.6) 5 (29.4) 5 (50.0)    
No. of drugs to which isolate is resistant     0.015*   
 1 21(60) 6(35.3) 2(20.0)    
 2 9(25.7) 3(17.6) 1(10.0)    
 3 4(11.4) 5(29.5) 5(50.0)    
 4 1(2.9) 3(17.6) 2(20.0)    
Drug resistance patterns     0.003*   
 Non-MDR-TB 30 (85.7) 12 (70.6) 3 (30.0)   Reference  
 MDR-TB 5 (14.3) 5 (29.4) 7 (70.0)   8.3(1.7–39.9) 0.008
  1. * P value was determined by Fisher’s Exact Test