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Fig. 6 | BMC Pulmonary Medicine

Fig. 6

From: Impaired nuclear factor erythroid 2-related factor 2 expression increases apoptosis of airway epithelial cells in patients with chronic obstructive pulmonary disease due to cigarette smoking

Fig. 6

Effect of Nrf2 knock down on CSE induced apoptosis. a The siRNA-Nrf2 complex transfection with A549 cell significantly decreased Nrf2 mRNA expression in CTL and 15 % CSE. b Apoptotic index was increased over time in 10 % CSE or 10 % CSE with Nrf2 knockdown compared with CTL. *: p < 0.05 compared with CTL. c Apoptotic index was not significantly increased in 10 % CSE compared with CTL, while significantly increased in 10 % CSE with Nrf2 knockdown compared with CTL. CTL: control

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