Table 1 Acos according to Spanish and Gina guidelines

ACOS According to Spanish guidelines

1-very positive bronchodilator test (increase in FEV1 ≥ 15 % and ≥400 mL)

2-Eosinophilia in sputum

3-Personal history of asthma

1-High levels of total IgE

2-Personal history of atopy

3-Positive bronchodilator test on at least two occasions (increase of FEV1 > 12 % and >200 mL)

ACOS According to GINA guidelines

A similar number of features of both asthma and COPD, consider the diagnosis of ACOS