From: Analysis of mitochondrial DNA alteration in new phenotype ACOS
 | COPD | ACOS Spanish | Asthma | ACOS GINA | Healthy subjects | p | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
 | mean | ds | mean | ds | mean | ds | mean | ds | mean | ds |  |
Age | 72 | 4.78 | 67.11 | 6.39 | 60.67 | 12.30 | 61.80 | 6.25 | 61.18 | 3.72 | 0.0225 |
BMI | 29.45 | 4.29 | 28.88 | 4.46 | 28.86 | 5.63 | 29.70 | 5.85 | 27.80 | 4.64 | ns |
Atopy (n) | 0 | Â | 4 | Â | 10 | Â | 7 | Â | 0 | Â | Â |
FEV1 | 46.88 | 10.68 | 72.56 | 23.40 | 88.78 | 17.73 | 83.60 | 22.83 | 90.97 | 6.33 | 0.0006 |
REV | 6.37 | 2.26 | 18 | 8.48 | 18.89 | 7.63 | 19.60 | 4.81 | 0 | Â | 0.0004 |
Smoking habit: | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 smokers | 2 |  | 0 |  | 0 |  | 2 |  |  |  |  |
 ex smokers | 11 |  | 8 |  | 0 |  | 1 |  |  |  |  |
 never smokers | 0 |  | 2 |  | 14 |  | 10 |  | 0 |  |  |
 P/Y | 68.63 | 32.34 | 36.83 | 44.43 | 0 | 0 | 6.60 | 13 |  |  | <0.0001 |
FENO 50 | 17.63 | 4.24 | 23.33 | 14.84 | 21.89 | 11.60 | 27.30 | 14.80 | 10.23 | 3.50 | ns |
induced sputum eosinophils | 0.58 | 1.39 | 4.86 | 3.18 | 47.33 | 26.52 | 2.10 | 1.73 | 0.60 | 0.80 | <0.0001 |
induced sputum neutrophils | 88.66 | 10.80 | 82.86 | 10.64 | 24.44 | 20.16 | 81.20 | 11.39 | 27.30 | 13 | <0.0001 |