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Table 2 Demographic and Clinical data of patients enrolled

From: Analysis of mitochondrial DNA alteration in new phenotype ACOS

 

COPD

ACOS Spanish

Asthma

ACOS GINA

Healthy subjects

p

 

mean

ds

mean

ds

mean

ds

mean

ds

mean

ds

 

Age

72

4.78

67.11

6.39

60.67

12.30

61.80

6.25

61.18

3.72

0.0225

BMI

29.45

4.29

28.88

4.46

28.86

5.63

29.70

5.85

27.80

4.64

ns

Atopy (n)

0

 

4

 

10

 

7

 

0

  

FEV1

46.88

10.68

72.56

23.40

88.78

17.73

83.60

22.83

90.97

6.33

0.0006

REV

6.37

2.26

18

8.48

18.89

7.63

19.60

4.81

0

 

0.0004

Smoking habit:

           

 smokers

2

 

0

 

0

 

2

    

 ex smokers

11

 

8

 

0

 

1

    

 never smokers

0

 

2

 

14

 

10

 

0

  

 P/Y

68.63

32.34

36.83

44.43

0

0

6.60

13

  

<0.0001

FENO 50

17.63

4.24

23.33

14.84

21.89

11.60

27.30

14.80

10.23

3.50

ns

induced sputum eosinophils

0.58

1.39

4.86

3.18

47.33

26.52

2.10

1.73

0.60

0.80

<0.0001

induced sputum neutrophils

88.66

10.80

82.86

10.64

24.44

20.16

81.20

11.39

27.30

13

<0.0001

  1. BMI: body mass index, FEV1: forced expiratory volume in one 1 s, REV: reversibility of FEV1 after bronchodilatation test with salbutamol, P/Y: pack/year, FENO 50: Fraction of exhaled nitic oxide at 50 ml/s