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Table 2 Univariate analyses of factors associated with corticosteroids responsiveness

From: Corticosteroids in treatment of aspiration-related acute respiratory distress syndrome: results of a retrospective cohort study

 

Response (n = 31,%)

Non-response (n = 16,%)

P value

Age (years)

65.8 (SD 9.5)

67.1 (SD 14.2)

0.21

Sex male

21 (67.4)

13 (68.4)

0.49

NIHSS score

9.0 (SD 3.2)

9.3 (SD 2.8)

0.50

GCS score

6.0 (SD 2.1)

5.8 (SD 2.1)

0.72

Smoking

12 (38.7)

7 (43.6)

0.76

Excess alcohol consumption

9 (29.0)

5 (31.3)

1.00

Pre-existing illnesses

   

 Hypertension

22 (71.0)

11 (68.9)

0.90

 Diabetes

16 (51.6)

8 (50.0)

0.17

 Coronary heart disease

6 (19.4)

3 (18.9)

1.00

Chest CT

   

 GGOs

23 (74.2)

7 (43.8)

0.04

 Consolidation opacities

16 (51.6)

9 (56.3)

1.00

 Pleural effusions

10 (32.3)

4 (25.0)

0.74

 Air bronchogram

6 (19.4)

4 (25.0)

0.72

PaO2/FiO2 (mmHg)

139.5 (SD 55.5)

147.0 (SD 63.0)

0.99

APACHE II score

27.4 (SD 13.6)

28.4 (SD 11.1)

0.54

pH value

7.40 (SD 0.6)

7.38 (SD 0.5)

0.41

Albumin (g/L)

26.6 (SD 7.9)

27.9 (SD 8.3)

0.88

Time from diagnosis to corticosteroids (days)

5.5 (SD 2.0)

6.0 (SD 2.5)

0.16

  1. Abbreviation: SD standard deviation, NIHSS National Institutes of Health Stroke Scale, GCS Glasgow Coma Scale, GGOs ground glass opacities, APACHE Acute Physiology and Chronic Health Evaluation, PaO 2 partial pressure of oxygen in arterial blood, FiO 2 fraction of inspired oxygen