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Table 1 Characteristics of the patients (N = 6,981) according to vital statusa (N = 6,981)

From: Early mortality in lung cancer: French prospective multicentre observational study

  

Vital status at

  

1 month

 

3 months

 
  

Alive

Dead

 

Alive

Dead

 
 

N

N = 6,303

N = 678

p-value

N = 5,360

N = 1,621

p-value

Sex

 

n = 6,303

n = 678

0.018

n = 5,360

n = 1,621

0.097

 Men, n (%)

5,286

4,747 (75.3)

539 (79.5)

 

4,033 (75.2)

1,253 (77.3)

 

 Women, n (%)

1,695

1,556 (24.7)

139 (20.5)

 

1,327 (24.8)

368 (22.7)

 

Age

 

n = 6,303

n = 678

<0.001

n = 5,360

n = 1,621

<0.001

 ≤40 years, n (%)

73

66 (1.1)

7 (1.0)

 

61 (1.1)

12 (0.7)

 

 41-50 years, n (%)

536

502 (8.0)

34 (5.0)

 

448 (8.4)

88 (5.4)

 

 51-60 years, n (%)

1,876

1,730 (27.5)

146 (21.5)

 

1,519 (28.3)

357 (22.0)

 

 61-70 years, n (%)

2,053

1,865 (29.6)

188 (27.7)

 

1,612 (30.1)

441 (27.2)

 

 71-80 years, n (%)

1,713

1,530 (24.3)

183 (27.0)

 

1,260 (23.5)

453 (28.0)

 

 >80 years, n (%)

730

610 (9.7)

120 (17.7)

 

460 (8.6)

270 (16.7)

 

Age (years)

 

n = 6,303

n = 678

<0.001

n = 5,360

n = 1,621

<0.001

 Mean (SD)

 

65.2 (11.2)

68.2 (11.7)

 

64.7 (11)

68.2 (11.7)

 

 Median (Q1-Q3)

 

65 (57-74)

68 (60-78)

 

64 (57-73)

68 (60-78)

 

 Body mass index (BMI; kg/m2)

 

n = 5,974

n = 558

<0.001

n = 5,139

n = 1,393

<0.001

 Mean (SD)

 

24.4 (4.8)

23.5 (4.8)

 

24.6 (4.8)

23.3 (4.7)

 

 Median (Q1-Q3)

 

23.9 (21-27.1)

23.2 (20.3-26.3)

 

24.1 (21.2-27.3)

22.9 (20.1-26.1)

 

Weight loss within the last 3 months

 

n = 6,154

n = 625

<0.001

n = 5,249

n = 1,530

<0.001

 No, n (%)

3,143

2,985 (48.5)

158 (25.3)

 

2,717 (51.8)

426 (27.8)

 

 Yes, n (%)

3,636

3,169 (51.5)

467 (74.7)

 

2,532 (48.2)

1,104 (72.2)

 

If yes

 

n = 3111

n = 446

<0.001

n = 2,493

n = 1,064

<0.001

 <5 kg, n (%)

1,489

1,340 (43.1)

149 (33.4)

 

1,141 (45.8)

348 (32.7)

 

 5-10 kg, n (%)

1,452

1,270 (40.8)

182 (40.8)

 

1,005 (40.3)

447 (42.0)

 

 ≥10 kg, n (%)

616

501 (16.1)

115 (25.8)

 

347 (13.9)

269 (25.3)

 

Performance status at diagnosis

 

n = 6,235

n = 672

<0.001

n = 5,299

n = 1,608

<0.001

 0- Fully active, n (%)

1,885

1,855 (29.8)

30 (4.5)

 

1,765 (33.3)

120 (7.5)

 

 1- Restricted in heavy physical work, n (%)

2,872

2,749 (44.1)

123 (18.3)

 

2,462 (46.5)

410 (25.5)

 

 2- Up and about more than half the day, n (%)

1,273

1,103 (17.7)

170 (25.3)

 

812 (15.3)

461 (28.7)

 

 3- In bed or sitting in a chair more than half the day, n (%)

685

460 (7.4)

225 (33.5)

 

231 (4.4)

454 (28.2)

 

 4- In bed or in a chair all the time, n (%)

192

68 (1.1)

124 (18.5)

 

29 (0.6)

163 (10.1)

 

Smoking status

 

n = 6,271

n = 668

0.831

n = 5,335

n = 1,604

0.803

 Never-smoker, n (%)

752

679 (10.8)

73 (10.9)

 

583 (10.9)

169 (10.5)

 

 Former-smoker, n (%)

2,776

2,516 (40.1)

260 (38.9)

 

2,124 (39.8)

652 (40.7)

 

 Active-smoker, n (%)

3,411

3,076 (49.1)

335 (50.2)

 

2,628 (49.3)

783 (48.8)

 

Tobacco consumption (pack-years)b

5,893

n = 5,352

n = 541

0.003

n = 4,566

n = 1,327

<0.001

 Mean (SD)

 

42.8 (21.3)

45.3 (22.4)

 

42.5 (21)

44.9 (22.8)

 

 Median (Q1-Q3)

 

40 (30-50)

40 (30-55)

 

40 (30-50)

40 (30-54)

 

Tobacco duration (years)b

5,220

n = 4,763

n = 457

0.015

n = 4,067

n = 1,153

<0.001

 Mean (SD)

 

37.4 (11.6)

38.7 (11.5)

 

37.2 (11.6)

38.5 (11.6)

 

 Median (Q1-Q3)

 

40 (30-45)

40 (30-46)

 

39 (30-45)

40 (30-45)

 
  1. a1 and 3 months after the diagnosis of primary lung cancer (date of diagnosis = date of histological or cytological sampling);
  2. bSmokers (former or active) only
  3. N or n: number of subjects; Q1-Q3: First and third quartiles; SD: standard deviation
  4. Note: Significant p-value are in bold