Table 3 Blood leukocyte counts and systemic inflammatory markers of asthmatics classified by phenotypes and healthy subjects

Blood leukocytes (x 10³/μL)

7.76 (6.52–8.87)^‡

7.75 (6.43–10.00)^‡

8.02 (6.16–10.83)^‡

7.25 (6.02–8.75)^‡

6.12 (5.03–7.37)

0.0001

Blood eosinophils

 /μL

315 (202–513)^‡*

129 (79–228)^†§

289 (216–449)^‡*

140 (85–227)^‡

106 (68–172)

0.0001

 %

4.2 (2.8–6.2)^‡*

1.7 (1.0–3.0)^†§

3.9 (2.7–5.8)^‡*

2.0 (1.1–3.0)

1.8 (1.0–3.0)

0.0001

Blood neutrophils

 /μL

4045 (3204–5140)^‡

4847 (3260–6323)^‡*†

4207 (2834–6610)

3971 (3156–5280)^‡

3416 (2610–4188)

0.0001

 %

54.0 (47.6–60.1)^*

59.5 (52.5–69.3)^*†

57.6 (44.4–62.4)

56.5 (50.3–62.2)

54.4 (49.6–62.1)

0.0001

Blood monocytes

 /μL

515 (396–667)^‡*

492 (408–656)^‡

564 (448–775)^‡

461 (362–608)

399 (330–550)

0.0001

 %

6.7 (5.1–8.3)

6.5 (5.4–8.2)

7.2 (5.6–9.0)

6.4 (5.1–8.2)

7.1 (5.7–8.2)

>0.05

Blood lymphocytes

 /μL

2358 (1918–2809)^‡

2249 (1765–2807)

2180 (1887–2869)

2337 (1894–2904)^‡

2009 (1611–2386)

0.0001

 %

31.8 (26.0–38.3)

29.4 (22.5–37.1)^‡*

29.1 (21.0–38.2)

32.7 (27.3–38.2)

33.9 (26.5–37.7)

0.006

Blood basophils

 /μL

42 (29–63)^‡*

35 (23–51)^†

39 (27–55)

34 (24–52)

34 (24–46)

0.0001

 %

0.6 (0.4–0.8)^*

0.5 (0.3–0.6)^‡†

0.5 (0.4–0.7)

0.5 (0.3–0.7)

0.5 (0.4–0.8)

0.0001

CRP (mg/L)^b

1.4 (0.6–3.6)

1.9 (0.8–5.3)^‡

2.9 (0.6–8.9)

1.6 (0.6–4.5)

1.1 (0.4–2.4)

0.034

Fibrinogen (g/L)^c

3.2 (2.8–3.8)^‡

3.2 (2.8–3.7)^‡

3.3 (2.7–3.9)

3.1 (2.7–3.6)

2.9 (2.6–3.2)

0.0008