Ā | Paucigranulocytic asthma, not treated with ICS | Paucigranulocytic asthma, treated with ICS | ICS- vs ICS+ | Neutrophilic asthma, not treated with ICS | Neutrophilic asthma, treated with ICS | ICS- vs ICS+ | Healthy subjects |
---|---|---|---|---|---|---|---|
N | 123 | 195 | - | 47 | 87 | - | 194 |
Sputum total non-squamous cell count (x 106/g) | 0.93 (0.43ā2.12) | 0.69 (0.36ā1.61) | NS | 1.45 (0.82ā4.65)ā” | 2.10 (0.75ā8.02)ā” | NS | 0.64 (0.37ā1.30) |
Sputum viability (%) | 65 (48ā78) | 64 (48ā75) | NS | 78 (68ā87)ā” | 80 (68ā88)ā” | NS | 67 (53ā78) |
Sputum squamous cells (%) | 16 (7ā30) | 19 (10ā37) | NS | 18 (5ā30) | 7 (2ā27)ā” | NS | 18 (10ā31) |
Sputum eosinophils (x 103/g) | 4 (0ā15)ā” | 2 (0ā10)ā” | NS | 2 (0ā28)ā” | 4 (0ā27)ā” | NS | 0 (0ā2) |
Sputum neutrophils (x 103/g) | 315 (97ā994) | 245 (86ā710) | NS | 1197 (707ā3776)ā” | 1879 (593ā7060)ā” | NS | 210 (63ā563) |
Sputum macrophages (x 103/g) | 451 (188ā864)ā” | 280 (154ā853) | NS | 127 (33ā396)ā” | 182 (52ā436) | NS | 285 (120ā568) |
Sputum lymphocytes (x 103/g) | 12 (3ā45) | 10 (2ā24) | NS | 15 (4ā41) | 11 (1ā39) | NS | 10 (4ā26) |
Sputum epithelial cells (x 103/g) | 48 (19ā113) | 52 (25ā120)ā” | NS | 19 (4ā44) | 18 (3ā73) | NS | 35 (12ā86) |
Blood leukocytes (x103/Ī¼L)a | 6.87 (5.85ā8.51)ā” | 7.47 (6.32ā9.06)ā” | NS | 7.87 (6.41ā9.93)ā” | 7.71 (6.44ā10.06)ā” | NS | 6.12 (5.03ā7.37) |
Blood eosinophils (/Ī¼L)a | 145 (101ā217)ā” | 139 (74ā229) | NS | 172 (63ā293) | 123 (80ā215) | NS | 106 (68ā172) |
Blood neutrophils (/Ī¼L)a | 3598 (2924ā5119) | 4211 (3392ā5392)ā” | NS | 4804 (3158ā6021)ā” | 4885 (3403ā6969)ā” | NS | 3416 (2610ā4188) |
Blood monocytes (/Ī¼L)a | 461 (353ā592) | 463 (370ā615)ā” | NS | 476 (387ā648) | 519 (419ā669)ā” | NS | 399 (330ā550) |
Blood lymphocytes (/Ī¼L)a | 2352 (1891ā2967)ā” | 2321 (1900ā2855)ā” | NS | 2518 (1989ā3035)ā” | 2167 (1675ā2726) | NS | 2009 (1611ā2386) |
Blood basophils (/Ī¼L)a | 35 (25ā52) | 33 (24ā51) | NS | 40 (29ā53) | 33 (22ā50) | NS | 34 (24ā46) |