Fig. 1
From: Role of CD248 as a potential severity marker in idiopathic pulmonary fibrosis
Panel a: Typical CD248 staining patterns in the fibrotic lung in a sample obtained by VATS biopsy from an IPF patient with mild/moderate fibrotic changes in the lung. Original magnification 40x.: Panel b: Typical CD248 staining in end-stage fibrosis in the lung sample of an IPF patient undergone lung transplantation. Original magnification 40x. Panel c: Pale CD248 staining (brown) in fibroblastic foci (arrows) compared to adjacent scarring (stars), (original magnification x200). Panel d: IHC staining of CD248 in IPF patient. The epithelium in dilated air spaces is negative for CD248 (arrow) while adjacent fibrotic stromal regions (stars) show pale to moderate CD248 staining. (original magnification x100). Slides were visualized using an Olympus BX51 microscope (Olympus) and photographed with an Olympus C3030 camera (Olympus)