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Table 3 Clinical factors associated with abnormal lung functions

From: Lung functions among patients with pulmonary tuberculosis in Dar es Salaam – a cross-sectional study

Characteristics

Total

Any Abnormality

P

Obstructive

P

Restrictive

P

 

Mixed

P

MMRC score (number, %)

 1–2

407

292

71.7 %

0.013*

173

59.2 %

0.04*

53

18.2 %

0.868*

66

22.6 %

0.00

 3–5

94

79

84 %

 

36

45.6 %

 

13

16.5 %

 

30

38.0 %

9*

Cigarette smoking (number, %)

 Never smokers

354

255

72.0 %

0.118*

151

59.2 %

0.114*

49

19.2 %

0.309*

55

21.6 %

0.00

 Ever Smokers

147

116

78.9 %

 

58

50.0 %

 

17

14.7 %

 

41

35.3 %

7*

Smoking Pack Years (number, %) (n=147)

 ≤5

107

86

80.4 %

0.5*

36

41.9 %

0.005*

16

18.6 %

0.068*

34

39.5 %

0.12

 >5

40

30

75.0 %

 

22

73.3 %

 

1

3.3 %

 

7

23.3 %

6*

Smear for Acid Fast Bacilli (number, %)

 Smear Positive

272

198

72.8 %

0.54*

110

55.6 %

0.754*

31

15.7 %

0.278*

57

28.8 %

0.19

 Smear Negative

229

173

75.5 %

 

99

57.2 %

 

35

20.2 %

 

39

22.5 %

2*

Time to Negative Sputum Conversion (number, %)

 Smear Positive at 2 Months

27

19

70.4 %

0.82*

11

57.9 %

1.0*

3

15.8 %

1.0*

 

26.3 %

1.0*

 Smear Negative at 2 Months

245

179

73.1 %

 

99

55.3 %

 

28

15.6 %

  

29.1 %

 

TB Episode Number (number, %)

 First

426

304

71.4 %

0.001*

171

56.3 %

1.0*

59

19.4 %

0.111*

74

24.3 %

0.16

 Recurrent

75

67

89.3 %

 

38

56.7 %

 

7

10.4 %

 

22

32.8 %

6*

Duration to TB diagnosis (mo) (number, %)

 ≤1 Month

275

207

75.3

0.539*

117

56.5 %

1.0*

40

19.3 %

0.414*

50

24.2 %

0.40

 >1 Month

226

164

72.6

 

92

56.1 %

 

26

15.9 %

 

46

28.0 %

6*

HIV Status (number, %)

 HIV Positive

152

102

67.1 %

0.026*

68

66.7 %

0.014*

17

16.7 %

0.764*

17

16.7 %

0.01

 HIV Negative

349

269

77.1 %

 

141

52.4 %

 

49

18.2 %

 

79

29.4 %

2*

 CD4 count (Median (IQR))

 

202.50 (210)

  

192.5 (225)

 

200 (156)

 

260(167)

 
  1. * fishers exact, MMRC score Modified Medical Research Council Dyspnea score, BMI Body Mass Index, IQR Interquartile range