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Table 3 Clinical factors associated with abnormal lung functions

From: Lung functions among patients with pulmonary tuberculosis in Dar es Salaam – a cross-sectional study

Characteristics Total Any Abnormality P Obstructive P Restrictive P   Mixed P
MMRC score (number, %)
 1–2 407 292 71.7 % 0.013* 173 59.2 % 0.04* 53 18.2 % 0.868* 66 22.6 % 0.00
 3–5 94 79 84 %   36 45.6 %   13 16.5 %   30 38.0 % 9*
Cigarette smoking (number, %)
 Never smokers 354 255 72.0 % 0.118* 151 59.2 % 0.114* 49 19.2 % 0.309* 55 21.6 % 0.00
 Ever Smokers 147 116 78.9 %   58 50.0 %   17 14.7 %   41 35.3 % 7*
Smoking Pack Years (number, %) (n=147)
 ≤5 107 86 80.4 % 0.5* 36 41.9 % 0.005* 16 18.6 % 0.068* 34 39.5 % 0.12
 >5 40 30 75.0 %   22 73.3 %   1 3.3 %   7 23.3 % 6*
Smear for Acid Fast Bacilli (number, %)
 Smear Positive 272 198 72.8 % 0.54* 110 55.6 % 0.754* 31 15.7 % 0.278* 57 28.8 % 0.19
 Smear Negative 229 173 75.5 %   99 57.2 %   35 20.2 %   39 22.5 % 2*
Time to Negative Sputum Conversion (number, %)
 Smear Positive at 2 Months 27 19 70.4 % 0.82* 11 57.9 % 1.0* 3 15.8 % 1.0*   26.3 % 1.0*
 Smear Negative at 2 Months 245 179 73.1 %   99 55.3 %   28 15.6 %    29.1 %  
TB Episode Number (number, %)
 First 426 304 71.4 % 0.001* 171 56.3 % 1.0* 59 19.4 % 0.111* 74 24.3 % 0.16
 Recurrent 75 67 89.3 %   38 56.7 %   7 10.4 %   22 32.8 % 6*
Duration to TB diagnosis (mo) (number, %)
 ≤1 Month 275 207 75.3 0.539* 117 56.5 % 1.0* 40 19.3 % 0.414* 50 24.2 % 0.40
 >1 Month 226 164 72.6   92 56.1 %   26 15.9 %   46 28.0 % 6*
HIV Status (number, %)
 HIV Positive 152 102 67.1 % 0.026* 68 66.7 % 0.014* 17 16.7 % 0.764* 17 16.7 % 0.01
 HIV Negative 349 269 77.1 %   141 52.4 %   49 18.2 %   79 29.4 % 2*
 CD4 count (Median (IQR))   202.50 (210)    192.5 (225)   200 (156)   260(167)  
  1. * fishers exact, MMRC score Modified Medical Research Council Dyspnea score, BMI Body Mass Index, IQR Interquartile range