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Fig. 4 | BMC Pulmonary Medicine

Fig. 4

From: Extracellular microRNA-21 and microRNA-26a increase in body fluids from rats with antigen induced pulmonary inflammation and children with recurrent wheezing

Fig. 4

MiR-21 and miR-26a level in body fluids and solid organs from rats with antigen induced pulmonary inflammation. a-b miR-21 (a) and miR-26a (b) in plasma, BALF, spleens and lavaged lungs of rats from control, acute and chronic AIPI rats. c Total cell counts in BALF of AIPI rats. d Scatter dot plots of correlation between plasma and lung miR-21. e Scatter dot plots of correlation between BALF miR-21 (miR-26a) and BALF cell counts. BALF stands for bronchoalveolar lavage fluid. RT-qPCR was used to determine the miRNA levels. Cel-miR-39 and U6 snRNA were used as internal controls for circulating or intrinsic miRNA detection. Data were analyzed by Kruskal-Wallis test followed with Mann-Whitney test for analysis between groups. Spearman correlation method was used for correlation analysis. *: p < 0.05, **: p < 0.01, ***: p < 0.001

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