Fig. 2

Change from test-day baseline (SE) in FEV₁ AUC_0–6 and peak FEV₁ after 4 weeks. Mean (adjusted) change and post-hoc analysis of mean ratio of change from test-day baseline (SE) in FEV₁ AUC_0–6 and peak FEV₁ after 4 weeks using the mixed-effect model repeated measures (MMRM). a Mean (adjusted) change from test-day baseline in FEV₁ AUC 0–6 (ml) (95 % CI of the difference: (0.058, 0.112) p <0.0001); b Mean ratio of change from test-day baseline in FEV1 AUC0-6 (%) (95 % CI of the difference: (0.032, 0.061) p <0.0001); c Mean (adjusted) change from test-day baseline in peak FEV₁ (ml) (95 % CI of the difference: (0.047, 0.107) p <0.0001); d Mean ratio of change from test-day baseline in peak FEV₁ (%) (95 % CI of the difference: (0.027, 0.060) p <0.0001)