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Table 5 Hazard ratios of diabetes mellitus by quartiles of FEV1%predicted in males: sub-cohort further adjusted for inflammation (5133 men)

From: The temporal relationship between poor lung function and the risk of diabetes

follow-up time (years) (n = number of incident DM events)   Q4 (reference) Q3 Q2 Q1 P value for trend
   ≥106.39 95.20–106.39 83.51–95.17 ≤83.50  
Follow-up time 0–37 years (n = 1025) Adjusted riska 1.00 0.94 (0.78–1.13) 1.24 (1.04–1.48)* 1.36 (1.14–1.63)** <0.001
Further adjusted for inflammationb 1.00 0.91 (0.75–1.09) 1.20 (1.01–1.44)* 1.29 (1.07–1.54)** <0.001
  1. aAdjusted for: age, height, BMI, smoking status, baseline glucose, cholesterol, physical activity, BP medication, social class, family history of diabetes, alcohol abuse bFurther adjusted for ESR (log transformed), WCC, Fibrinogen, complement C3, haptoglobin, ceruloplasmin, alpha-1 antitrypsin, and orosomucoid. *p <0.05 **p < 0.01. P value for trend calculated using cox regression models (1 d.f)