From: CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development
Mean ± S.D. | Median (IQR) | Range | N (%) | |
---|---|---|---|---|
Anthropometrics at birtha | ||||
Gestational age weeks | 39.7 ± 1.1 | 40 (39.1–40.7) | 37.0–42.0 | |
Weight kg | 3.4 ± 0.4 | 3.4 (3.1–3.7) | 2.2–4.9 | |
Length cm | 49.5 ± 1.9 | 50.0 (48–51) | 45–55 | |
Anthropometrics at follow-upa | ||||
Age years | 6.0 ± 0.3 | 6 (5.9–6.2) | 5.1– 6.9 | |
Weight kg | 22.7 ± 3.8 | 22.2 (20.0–24.5) | 16–35.8 | |
Length cm | 117.5 ± 5.6 | 117.5 (114–121) | (104–107) | |
YKL-40 in cord blooda | ||||
YKL-40 ng/ml | 42.4 ± 28.0 | 43.5 (23.3–63.3) | 0–97.2 | |
Clinical outcomes during the first yeara | ||||
Wks with daytime resp. sympt. | 4.6 ± 4.6 | 3 (1–7) | 0–24 | |
Wks with nighttime resp. sympt. | 3.8 ± 3.8 | 3 (1–6) | 0–21 | |
Wks with severe daytime resp. sympt. | 0.5 ± 0.9 | 0 (0–1) | 0–5 | |
Wks with severe nighttime resp. sympt. | 0.6 ± 1.1 | 0 (0–1) | 0–8 | |
Lung function at 5 weeksa | ||||
Tidal volume ml | 32.5 ± 5.5 | 32.5 (28.1–36.4) | 21–51 | |
Mean tidal expiratory flow | 43.3 ± 10.4 | 41.6 (35.7–49.3) | 21–79 | |
TPTEF/TE | 36.2 ± 10.8 | 34.7 (28.7–41.8) | 16–73 | |
Minute Ventilation ml · min−1 | 1427 ± 270 | 1405 (1239–1586) | 870–2333 | |
Clinical data at 6 years | ||||
Asthmab | 15 (12 %) | |||
Atopyc | 53 (39 %) | |||
Positive prick testd | 18 (17 %) | |||
Lung function at 6 years | ||||
FVC z-scoree | −0.41 ± 0.98 | −0.04 (−1.18–0.32) | −2.25–2.02 | |
FEV1 z-scoref | −0.09 ± 0.96 | −0.21 (−0.83–0.73) | −0.25–2.02 | |
FEF25–75% z-scoreg | −0.04 ± 0.94 | −0.04 (−0.68–0.55) | −2.95–2.27 |