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Table 1 Population characteristics and distribution of clinical outcomes

From: CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development

 

Mean ± S.D.

Median (IQR)

Range

N (%)

Anthropometrics at birtha

    

 Gestational age weeks

39.7 ± 1.1

40 (39.1–40.7)

37.0–42.0

 

 Weight kg

3.4 ± 0.4

3.4 (3.1–3.7)

2.2–4.9

 

 Length cm

49.5 ± 1.9

50.0 (48–51)

45–55

 

Anthropometrics at follow-upa

    

 Age years

6.0 ± 0.3

6 (5.9–6.2)

5.1– 6.9

 

 Weight kg

22.7 ± 3.8

22.2 (20.0–24.5)

16–35.8

 

 Length cm

117.5 ± 5.6

117.5 (114–121)

(104–107)

 

YKL-40 in cord blooda

    

 YKL-40 ng/ml

42.4 ± 28.0

43.5 (23.3–63.3)

0–97.2

 

Clinical outcomes during the first yeara

    

 Wks with daytime resp. sympt.

4.6 ± 4.6

3 (1–7)

0–24

 

 Wks with nighttime resp. sympt.

3.8 ± 3.8

3 (1–6)

0–21

 

 Wks with severe daytime resp. sympt.

0.5 ± 0.9

0 (0–1)

0–5

 

 Wks with severe nighttime resp. sympt.

0.6 ± 1.1

0 (0–1)

0–8

 

Lung function at 5 weeksa

    

 Tidal volume ml

32.5 ± 5.5

32.5 (28.1–36.4)

21–51

 

 Mean tidal expiratory flow

43.3 ± 10.4

41.6 (35.7–49.3)

21–79

 

 TPTEF/TE

36.2 ± 10.8

34.7 (28.7–41.8)

16–73

 

 Minute Ventilation ml · min−1

1427 ± 270

1405 (1239–1586)

870–2333

 

Clinical data at 6 years

    

 Asthmab

   

15 (12 %)

 Atopyc

   

53 (39 %)

 Positive prick testd

   

18 (17 %)

Lung function at 6 years

    

 FVC z-scoree

−0.41 ± 0.98

−0.04 (−1.18–0.32)

−2.25–2.02

 

 FEV1 z-scoref

−0.09 ± 0.96

−0.21 (−0.83–0.73)

−0.25–2.02

 

 FEF25–75% z-scoreg

−0.04 ± 0.94

−0.04 (−0.68–0.55)

−2.95–2.27

 
  1. FEV 1 Forced expiratory volume in 1 s, FVC Forced vital capacity, FEF 25–75% Forced expiratory flow at 25–75 % of FVC, IQR Interquartile range, N Number, S.D. Standard deviation, Wks Weeks, resp. sympt Respiratory symptoms. Data are given as mean (S.D.) median (IQR) or number (percentage) of infants. aData on = 142 infants. bMissing data on n = 7; data available for n = 135. cMissing data on n = 4; data available for n = 138. dMissing data on n = 38; data available for n = 104. eMissing data on n = 51; data available for n = 91. fMissing data on n = 66; data available for n = 76. gMissing data on n = 62; data available for n = 80