Skip to main content

Table 1 Population characteristics and distribution of clinical outcomes

From: CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development

  Mean ± S.D. Median (IQR) Range N (%)
Anthropometrics at birtha     
 Gestational age weeks 39.7 ± 1.1 40 (39.1–40.7) 37.0–42.0  
 Weight kg 3.4 ± 0.4 3.4 (3.1–3.7) 2.2–4.9  
 Length cm 49.5 ± 1.9 50.0 (48–51) 45–55  
Anthropometrics at follow-upa     
 Age years 6.0 ± 0.3 6 (5.9–6.2) 5.1– 6.9  
 Weight kg 22.7 ± 3.8 22.2 (20.0–24.5) 16–35.8  
 Length cm 117.5 ± 5.6 117.5 (114–121) (104–107)  
YKL-40 in cord blooda     
 YKL-40 ng/ml 42.4 ± 28.0 43.5 (23.3–63.3) 0–97.2  
Clinical outcomes during the first yeara     
 Wks with daytime resp. sympt. 4.6 ± 4.6 3 (1–7) 0–24  
 Wks with nighttime resp. sympt. 3.8 ± 3.8 3 (1–6) 0–21  
 Wks with severe daytime resp. sympt. 0.5 ± 0.9 0 (0–1) 0–5  
 Wks with severe nighttime resp. sympt. 0.6 ± 1.1 0 (0–1) 0–8  
Lung function at 5 weeksa     
 Tidal volume ml 32.5 ± 5.5 32.5 (28.1–36.4) 21–51  
 Mean tidal expiratory flow 43.3 ± 10.4 41.6 (35.7–49.3) 21–79  
 TPTEF/TE 36.2 ± 10.8 34.7 (28.7–41.8) 16–73  
 Minute Ventilation ml · min−1 1427 ± 270 1405 (1239–1586) 870–2333  
Clinical data at 6 years     
 Asthmab     15 (12 %)
 Atopyc     53 (39 %)
 Positive prick testd     18 (17 %)
Lung function at 6 years     
 FVC z-scoree −0.41 ± 0.98 −0.04 (−1.18–0.32) −2.25–2.02  
 FEV1 z-scoref −0.09 ± 0.96 −0.21 (−0.83–0.73) −0.25–2.02  
 FEF25–75% z-scoreg −0.04 ± 0.94 −0.04 (−0.68–0.55) −2.95–2.27  
  1. FEV 1 Forced expiratory volume in 1 s, FVC Forced vital capacity, FEF 25–75% Forced expiratory flow at 25–75 % of FVC, IQR Interquartile range, N Number, S.D. Standard deviation, Wks Weeks, resp. sympt Respiratory symptoms. Data are given as mean (S.D.) median (IQR) or number (percentage) of infants. aData on = 142 infants. bMissing data on n = 7; data available for n = 135. cMissing data on n = 4; data available for n = 138. dMissing data on n = 38; data available for n = 104. eMissing data on n = 51; data available for n = 91. fMissing data on n = 66; data available for n = 76. gMissing data on n = 62; data available for n = 80